Literature DB >> 29649766

microRNAs in the haemostatic system: More than witnesses of thromboembolic diseases?

Ana B Arroyo1, Ascensión M de Los Reyes-García1, Raúl Teruel-Montoya2, Vicente Vicente2, Rocío González-Conejero3, Constantino Martínez4.   

Abstract

MicroRNAs (miRNAs) are small endogenous RNAs that post-transcriptionally regulate gene expression. In the last few years, these molecules have been implicated in the regulation of haemostasis, and an increasing number of studies have investigated their relationship with the development of thrombosis. In this review, we discuss the latest developments regarding the role of miRNAs in the regulation of platelet function and secondary haemostasis. We also discuss the genetic and environmental factors that regulate miRNAs. Finally, we address the potential use of miRNAs as prognostic and diagnostic tools in thrombosis.
Copyright © 2018 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Biomarkers; Haemostasis; Regulation; Thrombosis; microRNAs

Mesh：

Substances：

Year:  2018        PMID： 29649766     DOI： 10.1016/j.thromres.2018.03.021

Source DB:  PubMed          Journal:  Thromb Res        ISSN： 0049-3848            Impact factor:   3.944


  7 in total

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Journal:  Cell Prolif       Date:  2018-07-20       Impact factor: 6.831

2.  Differential miRNA expression profile and proteome in plasma exosomes from patients with paroxysmal nocturnal hemoglobinuria.

Authors:  Raúl Teruel-Montoya; Ginés Luengo-Gil; Fernando Vallejo; José Enrique Yuste; Nataliya Bohdan; Nuria García-Barberá; Salvador Espín; Constantino Martínez; Juan Carlos Espín; Vicente Vicente; Irene Martínez-Martínez
Journal:  Sci Rep       Date:  2019-03-05       Impact factor: 4.379

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Journal:  Front Pediatr       Date:  2019-09-13       Impact factor: 3.418

4.  Bayesian network analysis of plasma microRNA sequencing data in patients with venous thrombosis.

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Review 7.  Role of microRNAs in Venous Thromboembolism.

Authors:  Vânia M Morelli; Sigrid K Brækkan; John-Bjarne Hansen
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  7 in total

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