Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Atrial natriuretic factor gene expression in ventricles of rats with spontaneous biventricular hypertrophy.

Literature DB >> 2963021

Atrial natriuretic factor gene expression in ventricles of rats with spontaneous biventricular hypertrophy.

R T Lee¹, K D Bloch, J M Pfeffer, M A Pfeffer, E J Neer, C E Seidman.

Abstract

A subset of Wistar-Kyoto (WKY) rats that spontaneously develops biventricular hypertrophy (BVH) in response to increased cardiac output was evaluated for ventricular expression of the atrial natriuretic factor (ANF) gene. Normal WKY rats had low levels of left ventricular ANF mRNA and minimally detectable ANF transcripts in the right ventricle. In contrast, BVH rats showed a sixfold greater ANF mRNA concentration in the left ventricle than age-matched WKY controls. BVH right ventricular ANF mRNA levels equaled those found in BVH left ventricles and were dramatically greater than WKY right ventricular controls. Unlike experimental models of hypertrophy, both left and right ventricles significantly increase ANF gene transcripts in the natural development of BVH. The left and right ventricles can concordantly respond to hypertrophy and increase ANF gene transcription.

Entities: Disease Gene Species

Mesh：

Substances：

Year: 1988 PMID： 2963021 PMCID： PMC329587 DOI： 10.1172/JCI113337

Source DB: PubMed Journal: J Clin Invest ISSN： 0021-9738 Impact factor: 14.808

13 in total

1. Physiology. The expanding physiological roles of atrial natriuretic factor.

Authors: P Needleman
Journal: Nature Date: 1986 May 15-21 Impact factor: 49.962

2. Extra-atrial expression of the gene for atrial natriuretic factor.

Authors: D G Gardner; C F Deschepper; W F Ganong; S Hane; J Fiddes; J D Baxter; J Lewicki
Journal: Proc Natl Acad Sci U S A Date: 1986-09 Impact factor: 11.205

3. The nucleotide sequence of a rat 18 S ribosomal ribonucleic acid gene and a proposal for the secondary structure of 18 S ribosomal ribonucleic acid.

Authors: Y L Chan; R Gutell; H F Noller; I G Wool
Journal: J Biol Chem Date: 1984-01-10 Impact factor: 5.157

4. Cardiac function and morphology with aging in the spontaneously hypertensive rat.

Authors: J M Pfeffer; M A Pfeffer; M C Fishbein; E D Frohlich
Journal: Am J Physiol Date: 1979-10

5. The structure of rat preproatrial natriuretic factor as defined by a complementary DNA clone.

Authors: C E Seidman; A D Duby; E Choi; R M Graham; E Haber; C Homcy; J A Smith; J G Seidman
Journal: Science Date: 1984-07-20 Impact factor: 47.728

6. Natural biventricular hypertrophy in normotensive rats. I. Physical and hemodynamic characteristics.

Authors: M A Pfeffer; J M Pfeffer; F G Dunn; K Nishiyama; M Tsuchiya; E D Frohlich
Journal: Am J Physiol Date: 1979-04

7. Atrial natriuretic factor--a circulating hormone stimulated by volume loading.

Authors: R E Lang; H Thölken; D Ganten; F C Luft; H Ruskoaho; T Unger
Journal: Nature Date: 1985 Mar 21-27 Impact factor: 49.962

8. Ventricular atriopeptin. Unmasking of messenger RNA and peptide synthesis by hypertrophy or dexamethasone.

Authors: M L Day; D Schwartz; R C Wiegand; P T Stockman; S R Brunnert; H E Tolunay; M G Currie; D G Standaert; P Needleman
Journal: Hypertension Date: 1987-05 Impact factor: 10.190

9. Myocardial recruitment during ANF mRNA increase with volume overload in the rat.

Authors: A L Lattion; J B Michel; E Arnauld; P Corvol; F Soubrier
Journal: Am J Physiol Date: 1986-11

10. Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease.

Authors: J M Chirgwin; A E Przybyla; R J MacDonald; W J Rutter
Journal: Biochemistry Date: 1979-11-27 Impact factor: 3.162

29 in total

1. Identification of a cis-acting regulatory element conferring inducibility of the atrial natriuretic factor gene in acute pressure overload.

Authors: R von Harsdorf; J G Edwards; Y T Shen; R K Kudej; R Dietz; L A Leinwand; B Nadal-Ginard; S F Vatner
Journal: J Clin Invest Date: 1997-09-01 Impact factor: 14.808

2. Remodeling of the peripheral cardiac conduction system in response to pressure overload.

Authors: Brett S Harris; Catalin F Baicu; Nicole Haghshenas; Harinath Kasiganesan; Dimitri Scholz; Mary S Rackley; Lucile Miquerol; Daniel Gros; Rupak Mukherjee; Terrence X O'Brien
Journal: Am J Physiol Heart Circ Physiol Date: 2012-02-03 Impact factor: 4.733

3. Nitric oxide decreases stability of mRNAs encoding soluble guanylate cyclase subunits in rat pulmonary artery smooth muscle cells.

Authors: G Filippov; D B Bloch; K D Bloch
Journal: J Clin Invest Date: 1997-08-15 Impact factor: 14.808

4. Expression of immediate early genes, GATA-4, and Nkx-2.5 in adrenergic-induced cardiac hypertrophy and during regression in adult mice.

Authors: N Saadane; L Alpert; L E Chalifour
Journal: Br J Pharmacol Date: 1999-07 Impact factor: 8.739

5. Knockout and knockin of the beta1 exon D define distinct roles for integrin splice variants in heart function and embryonic development.

Authors: C Baudoin; M J Goumans; C Mummery; A Sonnenberg
Journal: Genes Dev Date: 1998-04-15 Impact factor: 11.361

6. The neuron-restrictive silencer element-neuron-restrictive silencer factor system regulates basal and endothelin 1-inducible atrial natriuretic peptide gene expression in ventricular myocytes.

Authors: K Kuwahara; Y Saito; E Ogawa; N Takahashi; Y Nakagawa; Y Naruse; M Harada; I Hamanaka; T Izumi; Y Miyamoto; I Kishimoto; R Kawakami; M Nakanishi; N Mori; K Nakao
Journal: Mol Cell Biol Date: 2001-03 Impact factor: 4.272