Siamak Yousefi1,2, Hiroshi Sakai3, Hiroshi Murata1, Yuri Fujino1, David Garway-Heath4, Robert Weinreb5, Ryo Asaoka1. 1. Department of Ophthalmology, University of Tokyo, Tokyo, Japan. 2. Department of Ophthalmology, University of Tennessee Health Science Center, Memphis, Tennessee, United States. 3. Department of Ophthalmology, Graduate School of Medicine, University of the Ryukyus, Nishihara, Okinawa, Japan. 4. National Institute for Health Research Biomedical Research Centre at Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, London, United Kingdom. 5. Hamilton Glaucoma Center, Shiley Eye Institute and the Department of Ophthalmology, University of California San Diego, La Jolla, California, United States.
Abstract
Purpose: To compare the hemifield asymmetry of visual field (VF) loss in primary open-angle glaucoma (POAG) and primary angle-closure glaucoma (PACG) across all severity levels. Methods: A total of 522 eyes of 327 patients with POAG (mean age ± SD, 54.1 ± 12.4 years) and 375 eyes of 204 patients with PACG (67.3 ± 8.9 years) were included. Subjects meeting the definitions of POAG or PACG were included. Means of the total deviation (TD) values (Humphrey 24-2 VF) in the Glaucoma Hemifield Test (GHT) regions were calculated in early (≥ -6 dB), moderate (< -6 dB and ≥ -12 dB), and advanced (< -12 dB) stages of POAG and PACG eyes. Then the differences of the TD values between superior and inferior hemifield GHT regions of POAG and PACG eyes were calculated. Also, the relationship between the values of pattern SD (PSD) and mean TD (mTD) was compared between POAG and PACG. Results: In POAG eyes in the early stage, three regions (central, paracentral, and peripheral) in the superior hemifield had greater loss than their inferior counterparts; in moderate and advanced stages, all GHT regions in the superior hemifield had greater loss than their inferior counterparts. In PACG eyes, siginificantly fewer regions in the superior hemifield were significantly worse than their inferior counterpart, compared with POAG: one region (central) in early stage, two regions (central and peripheral) in moderate stage, and one region (central) in advanced stage. POAG eyes had greater PSD values than PACG eyes for given mean of TD values. Conclusions: In both POAG and PACG eyes, VF damage was more pronounced in superior hemifield than inferior hemifield; however, this tendency was more obvious in POAG eyes than in PACG eyes.
Purpose: To compare the hemifield asymmetry of visual field (VF) loss in primary open-angle glaucoma (POAG) and primary angle-closure glaucoma (PACG) across all severity levels. Methods: A total of 522 eyes of 327 patients with POAG (mean age ± SD, 54.1 ± 12.4 years) and 375 eyes of 204 patients with PACG (67.3 ± 8.9 years) were included. Subjects meeting the definitions of POAG or PACG were included. Means of the total deviation (TD) values (Humphrey 24-2 VF) in the Glaucoma Hemifield Test (GHT) regions were calculated in early (≥ -6 dB), moderate (< -6 dB and ≥ -12 dB), and advanced (< -12 dB) stages of POAG and PACG eyes. Then the differences of the TD values between superior and inferior hemifield GHT regions of POAG and PACG eyes were calculated. Also, the relationship between the values of pattern SD (PSD) and mean TD (mTD) was compared between POAG and PACG. Results: In POAG eyes in the early stage, three regions (central, paracentral, and peripheral) in the superior hemifield had greater loss than their inferior counterparts; in moderate and advanced stages, all GHT regions in the superior hemifield had greater loss than their inferior counterparts. In PACG eyes, siginificantly fewer regions in the superior hemifield were significantly worse than their inferior counterpart, compared with POAG: one region (central) in early stage, two regions (central and peripheral) in moderate stage, and one region (central) in advanced stage. POAG eyes had greater PSD values than PACG eyes for given mean of TD values. Conclusions: In both POAG and PACG eyes, VF damage was more pronounced in superior hemifield than inferior hemifield; however, this tendency was more obvious in POAG eyes than in PACG eyes.
Authors: Siamak Yousefi; Tobias Elze; Louis R Pasquale; Osamah Saeedi; Mengyu Wang; Lucy Q Shen; Sarah R Wellik; Carlos G De Moraes; Jonathan S Myers; Michael V Boland Journal: Ophthalmology Date: 2020-03-10 Impact factor: 12.079
Authors: Eunoo Bak; Young Kook Kim; Ahnul Ha; Young Soo Han; Jin-Soo Kim; Jinho Lee; Yong Woo Kim; Sung Uk Baek; Jin Wook Jeoung; Ki Ho Park Journal: Invest Ophthalmol Vis Sci Date: 2021-07-01 Impact factor: 4.799