Daniel J Taylor1, Alan L Peterson2,3,4, Kristi E Pruiksma2, Willie J Hale2,4, Stacey Young-McCaughan2, Allison Wilkerson5, Karin Nicholson6, Brett T Litz7,8,9, Katherine A Dondanville2, John D Roache2, Elisa V Borah1, Antoinette Brundige2, Jim Mintz2,10. 1. Department of Psychology, University of North Texas, Denton, TX. 2. Department of Psychiatry, University of Texas Health Science Center at San Antonio, San Antonio, TX. 3. Research and Development Service, South Texas Veterans Health Care System, San Antonio, TX. 4. Department of Psychology, University of Texas at San Antonio, San Antonio, TX. 5. Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, SC. 6. Department of Medicine, Carl R. Darnall Army Medical Center, Fort Hood, TX. 7. Massachusetts Veterans Epidemiological Research and Information Center, VA Boston Healthcare System, Boston, MA. 8. Department of Psychiatry, Boston University School of Medicine, Boston, MA. 9. Department of Psychological and Brain Sciences, Boston University, Boston, MA. 10. Department of Epidemiology and Biostatistics, University of Texas Health Science Center at San Antonio, San Antonio, TX.
Abstract
Study Objectives: To compare the efficacy of cognitive behavioral therapy for insomnia (CBTi) disorder and a Control condition on reducing insomnia and comorbid symptoms in a sample of active duty military personnel. Methods: Randomized clinical trial of 151 active duty US Army personnel at Fort Hood, Texas. Results: This study replicated Original (n = 66) findings (CBTi outperformed Control) in a follow-on sample (n = 85) on diary-assessed sleep efficiency (d = 1.04), total sleep time (d = 0.38), sleep latency (d = -0.93), number of awakenings (d = -0.56), wake time after sleep onset (d = -0.91), sleep quality (d = 1.00), and the Insomnia Severity Index (d = -1.36) in active duty soldiers. CBTi also outperformed Control in the combined sample (N = 151) on four of the five subscales of the Multidimensional Fatigue Inventory (d = -0.32 to -0.96) and the mental health subscale on the Veterans RAND 12-Item Health Survey (d = 0.37). Exploratory analyses also showed CBTi outperformed Control on nicotine (d = -0.22) and caffeine (d = -0.47) use reduction. Significant within-group differences were found for both groups on depression, anxiety, and posttraumatic stress disorder symptoms, but there was no group by time interaction for these symptoms or for use of hypnotics or alcohol. Conclusions: CBTi was an effective treatment for insomnia and comorbid symptoms including daytime fatigue, general mental health, nicotine, and caffeine use. Clinical Trial Registration: Clinicaltrials.gov; Identifier: NCT01549899; "Comparing Internet and In-Person Brief Cognitive Behavioral Therapy of Insomnia".
RCT Entities:
Study Objectives: To compare the efficacy of cognitive behavioral therapy for insomnia (CBTi) disorder and a Control condition on reducing insomnia and comorbid symptoms in a sample of active duty military personnel. Methods: Randomized clinical trial of 151 active duty US Army personnel at Fort Hood, Texas. Results: This study replicated Original (n = 66) findings (CBTi outperformed Control) in a follow-on sample (n = 85) on diary-assessed sleep efficiency (d = 1.04), total sleep time (d = 0.38), sleep latency (d = -0.93), number of awakenings (d = -0.56), wake time after sleep onset (d = -0.91), sleep quality (d = 1.00), and the Insomnia Severity Index (d = -1.36) in active duty soldiers. CBTi also outperformed Control in the combined sample (N = 151) on four of the five subscales of the Multidimensional Fatigue Inventory (d = -0.32 to -0.96) and the mental health subscale on the Veterans RAND 12-Item Health Survey (d = 0.37). Exploratory analyses also showed CBTi outperformed Control on nicotine (d = -0.22) and caffeine (d = -0.47) use reduction. Significant within-group differences were found for both groups on depression, anxiety, and posttraumatic stress disorder symptoms, but there was no group by time interaction for these symptoms or for use of hypnotics or alcohol. Conclusions: CBTi was an effective treatment for insomnia and comorbid symptoms including daytime fatigue, general mental health, nicotine, and caffeine use. Clinical Trial Registration: Clinicaltrials.gov; Identifier: NCT01549899; "Comparing Internet and In-Person Brief Cognitive Behavioral Therapy of Insomnia".
Authors: Emma C Lape; Lisa R LaRowe; Emily L Zale; Les A Gellis; Aesoon Park; Joseph W Ditre Journal: Exp Clin Psychopharmacol Date: 2021-02-25 Impact factor: 3.492
Authors: Adam D Cooper; Steven G Warner; Anna C Rivera; Rudolph P Rull; Amy B Adler; Dennis J Faix; Rob Neff; Edwin A Deagle; Ryan J Caserta; Cynthia A LeardMann Journal: PLoS One Date: 2020-06-03 Impact factor: 3.240
Authors: Anne Germain; Rachel R Markwald; Erika King; Adam D Bramoweth; Megan Wolfson; Gilbert Seda; Tony Han; Erin Miggantz; Brian O'Reilly; Lars Hungerford; Traci Sitzer; Vincent Mysliwiec; Joseph J Hout; Meredith L Wallace Journal: Trials Date: 2021-01-11 Impact factor: 2.279