Literature DB >> 29616151

Narcolepsy in Adolescence-A Missed Diagnosis: A Case Report.

Anoop K Gupta1, Swapnajeet Sahoo1, Sandeep Grover1.   

Abstract

Narcolepsy is an uncommon sleep cycle disorder with a usual onset in adolescence, but it is often misdiagnosed and underdiagnosed. Rarely is the tetrad of excessive daytime sleepiness, cataplexy, hypnagogic hallucinations, and sleep paralysis seen in patients. The clinical characteristics of narcolepsy are often confused with many psychiatric and neurologic disorders. Lack of clinical awareness about narcolepsy leads to frequent prescriptions of antiepileptics and psychotropics, which can adversely affect the quality of life of children and adolescents. We report a case of an adolescent male who presented with all four cardinal symptoms of narcolepsy and had been misdiagnosed with epilepsy, psychosis, and depression. We discuss various issues regarding narcolepsy in children and adolescents.

Entities:  

Keywords:  adolescence; misdiagnosis; narcolepsy

Year:  2017        PMID: 29616151      PMCID: PMC5880369     

Source DB:  PubMed          Journal:  Innov Clin Neurosci        ISSN: 2158-8333


  39 in total

Review 1.  Conditions of primary excessive daytime sleepiness.

Authors:  Jed E Black; Stephen N Brooks; Seiji Nishino
Journal:  Neurol Clin       Date:  2005-11       Impact factor: 3.806

2.  Stimulants and narcolepsy.

Authors:  Mark W Mahowald; Michel A Cramer Bornemann
Journal:  Sleep       Date:  2005-06       Impact factor: 5.849

Review 3.  Modafinil for narcolepsy: systematic review and meta-analysis.

Authors:  Dominik Golicki; Malgorzata M Bala; Maciej Niewada; Aleksandra Wierzbicka
Journal:  Med Sci Monit       Date:  2010-08

4.  Pandemic influenza vaccine & narcolepsy: simulations on the potential impact of bias.

Authors:  Leonoor Wijnans; Caitlin Dodd; Maria de Ridder; Silvana Romio; Daniel Weibel; Sebastiaan Overeem; Gert Jan Lammers; Jan Bonhoeffer; Steve Black; Miriam Sturkenboom
Journal:  Expert Rev Vaccines       Date:  2016-03-31       Impact factor: 5.217

5.  Low cerebrospinal fluid hypocretin (Orexin) and altered energy homeostasis in human narcolepsy.

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Journal:  Ann Neurol       Date:  2001-09       Impact factor: 10.422

Review 6.  Narcolepsy in adolescents.

Authors:  Shannon S Sullivan
Journal:  Adolesc Med State Art Rev       Date:  2010-12

Review 7.  The epidemiology of narcolepsy.

Authors:  W T Longstreth; Thomas D Koepsell; Thanh G Ton; Audrey F Hendrickson; Gerald van Belle
Journal:  Sleep       Date:  2007-01       Impact factor: 5.849

Review 8.  Narcolepsy, 2009 A(H1N1) pandemic influenza, and pandemic influenza vaccinations: what is known and unknown about the neurological disorder, the role for autoimmunity, and vaccine adjuvants.

Authors:  S Sohail Ahmed; Peter H Schur; Noni E MacDonald; Lawrence Steinman
Journal:  J Autoimmun       Date:  2014-02-19       Impact factor: 7.094

9.  HLA DQB1*06:02 negative narcolepsy with hypocretin/orexin deficiency.

Authors:  Fang Han; Ling Lin; Barbara Schormair; Fabio Pizza; Giuseppe Plazzi; Hanna M Ollila; Sona Nevsimalova; Poul Jennum; Stine Knudsen; Juliane Winkelmann; Cristin Coquillard; Farbod Babrzadeh; Tim M Strom; Chunlin Wang; Michael Mindrinos; Marcelo Fernandez Vina; Emmanuel Mignot
Journal:  Sleep       Date:  2014-10-01       Impact factor: 5.849

10.  Narcolepsy: a review.

Authors:  Gbolagade Sunmaila Akintomide; Hugh Rickards
Journal:  Neuropsychiatr Dis Treat       Date:  2011-09-08       Impact factor: 2.570

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  1 in total

Review 1.  Narcolepsy Presentation in Diverse Populations: an Update.

Authors:  Karen Spruyt
Journal:  Curr Sleep Med Rep       Date:  2020-11-25
  1 in total

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