| Literature DB >> 29610206 |
Lu Liu1,2,3, Yu Feng1,2,3, Haiyan Long1,2,3,4, Alan McNally4, Zhiyong Zong5,2,3.
Abstract
A carbapenem-resistant Klebsiella pneumoniae isolate was recovered from human blood. Its whole-genome sequence was obtained using Illumina and long-read MinION sequencing. The strain belongs to sequence type 273 (ST273), which was found recently and caused an outbreak in Southeast Asia. It has two carbapenemase genes, blaNDM-1 (carried by an ST7 IncN self-transmissible plasmid) and blaIMP-4 (located on a self-transmissible IncHI5 plasmid). Non-KPC-producing ST237 may represent a lineage of carbapenem-resistant K. pneumoniae, which warrants further monitoring.Entities:
Keywords: Klebsiella; Klebsiella pneumoniae; carbapenemases; carbapenems; plasmids; resistance; β-lactamases
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Year: 2018 PMID: 29610206 PMCID: PMC5971603 DOI: 10.1128/AAC.00160-18
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191