Literature DB >> 29610206

Sequence Type 273 Carbapenem-Resistant Klebsiella pneumoniae Carrying blaNDM-1 and blaIMP-4.

Lu Liu1,2,3, Yu Feng1,2,3, Haiyan Long1,2,3,4, Alan McNally4, Zhiyong Zong5,2,3.   

Abstract

A carbapenem-resistant Klebsiella pneumoniae isolate was recovered from human blood. Its whole-genome sequence was obtained using Illumina and long-read MinION sequencing. The strain belongs to sequence type 273 (ST273), which was found recently and caused an outbreak in Southeast Asia. It has two carbapenemase genes, blaNDM-1 (carried by an ST7 IncN self-transmissible plasmid) and blaIMP-4 (located on a self-transmissible IncHI5 plasmid). Non-KPC-producing ST237 may represent a lineage of carbapenem-resistant K. pneumoniae, which warrants further monitoring.
Copyright © 2018 American Society for Microbiology.

Entities:  

Keywords:  Klebsiella; Klebsiella pneumoniae; carbapenemases; carbapenems; plasmids; resistance; β-lactamases

Mesh:

Substances:

Year:  2018        PMID: 29610206      PMCID: PMC5971603          DOI: 10.1128/AAC.00160-18

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN: 0066-4804            Impact factor:   5.191


  22 in total

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10.  Emergence of Klebsiella pneumoniae ST273 Carrying blaNDM-7 and ST656 Carrying blaNDM-1 in Manila, Philippines.

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5.  Characterization of a bla NDM-1-Bearing IncHI5-Like Plasmid From Klebsiella pneumoniae of Infant Origin.

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6.  Characterization of the Plasmidome Encoding Carbapenemase and Mechanisms for Dissemination of Carbapenem-Resistant Enterobacteriaceae.

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