Literature DB >> 29607728

Pseudogout - a rare manifestation of hungry bone syndrome after focused parathyroidectomy.

C H Tai1, H B Oh1, J E Seet2, K Y Ngiam1.   

Abstract

Pseudogout, also known as calcium pyrophosphate deposition disease, is a rheumatological condition arising from accumulation of calcium pyrophosphate dihydrate crystals in connective tissues. We present a case of a 56-year-old Bangladeshi woman who underwent focused right inferior parathyroidectomy for primary hyperparathyroidism from a right inferior parathyroid adenoma. On the first post-operative day, she complained of left elbow painful swelling with redness and warmth. Arthrocentesis of left elbow was done due to suspicion of septic arthritis. Two weeks prior to this surgery, she had sudden bilateral knee swelling was diagnosed in her home country of bilateral knee osteoarthritis with effusion and arthrocentesis showed no crystals. Aspiration of left elbow showed calcium pyrophosphate crystals, associated with post parathyroidectomy hypocalcemia, hypomagnesemia confirming pseudogout. Her uric acid level was normal. Bilateral wrist x-rays showed triangular fibrocartilage complex chondrocalcinosis. The patient's condition improved with colchicine and naproxen, as well as calcium and magnesium replacement. Her left elbow swelling and pain resolved. Pseudogout flare is a rare but known sequelae after parathyroidectomy. Early recognition and expeditious treatment is essential.

Entities:  

Keywords:  Calcium pyrophosphate deposition disease; Chondrocalcinosis; Hyperparathyroidism; Parathyroid surgery; Parathyroidectomy; Pseudogout

Mesh:

Year:  2018        PMID: 29607728      PMCID: PMC5956596          DOI: 10.1308/rcsann.2018.0028

Source DB:  PubMed          Journal:  Ann R Coll Surg Engl        ISSN: 0035-8843            Impact factor:   1.891


  7 in total

1.  Chondrocalcinosis articularis Section L Clinical and radiological study.

Authors:  D ZITNAN; S SIT'AJ
Journal:  Ann Rheum Dis       Date:  1963-05       Impact factor: 19.103

2.  The significance of calcium phosphate crystals in the synovial fluid of arthritic patients: the "pseudogout syndrome". II. Identification of crystals.

Authors:  N N KOHN; R E HUGHES; D J McCARTY; J S FAIRES
Journal:  Ann Intern Med       Date:  1962-05       Impact factor: 25.391

3.  Clearance of calcium pyrophosphate dihydrate crystals in vivo. I. Studies using 169Yb labeled triclinic crystals.

Authors:  D J McCarty; D W Palmer; P B Halverson
Journal:  Arthritis Rheum       Date:  1979-07

4.  Crystal shedding and acute pseudogout. An hypothesis based on a therapeutic failure.

Authors:  R M Bennett; J R Lehr; D J McCarty
Journal:  Arthritis Rheum       Date:  1976 Jan-Feb

5.  Clinical studies of acute pseudogout attacks: comments on prevalence, predispositions, and treatment.

Authors:  J D O'Duffy
Journal:  Arthritis Rheum       Date:  1976 May-Jun

6.  Gout and coexisting pseudogout in the knee joint.

Authors:  Yonsik Yoo; Young-Jin Seo; Mina Huh; Je Hyun Yoo; Kyu Ho Yun; Sung-Jae Kim
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2010-08-28       Impact factor: 4.342

Review 7.  Hungry bone syndrome: still a challenge in the post-operative management of primary hyperparathyroidism: a systematic review of the literature.

Authors:  J E Witteveen; S van Thiel; J A Romijn; N A T Hamdy
Journal:  Eur J Endocrinol       Date:  2013-02-20       Impact factor: 6.664

  7 in total
  1 in total

1.  Giant Parathyroid Adenoma-Associated Fracture, Not All Lytic Bone Lesions are Cancer: A Case-Based Review.

Authors:  Jose C Alvarez-Payares; Marcel E Ribero; Sara Ramírez-Urrea; María C Fragozo-Ramos; Jose E Agámez-Gómez; Alejandro Román-González; Luis F Arias; Roberto Benavides Arenas; Fernando López-Urbano
Journal:  Case Rep Med       Date:  2022-01-29
  1 in total

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