| Literature DB >> 175804 |
R M Bennett, J R Lehr, D J McCarty.
Abstract
Four patients with chondrocalcinosis of the knees volunteered for joint lavage. Preliminary experiments indicated that disodium EDTA and magnesium ions were potent solubilizers of CPPD crystals. The procedure was a therapeutic failure in that insignificant amounts of CPPD were removed and all 4 subjects developed postlavage attacks of pseudogout. It is hypothesized that the acute attack of pseudogout is a result of crystal shedding and may be triggered by any factor that enhances CPPD solubility.Entities:
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Year: 1976 PMID： 175804 DOI： 10.1002/art.1780190116
Source DB: PubMed Journal: Arthritis Rheum ISSN： 0004-3591