BACKGROUND: Subcentimetre pulmonary nodules can be challenging to locate either during video-assisted thoracoscopic surgery (VATS) or by open techniques. In an era of increasing computed tomography scan availability the number of nodules that are identified that are suspicious for malignancy is rising, and thoracic surgeons require a reliable method to locate these nodules intraoperatively. METHODS: Our aim was to evaluate, for the first time in the UK, resection of pulmonary nodules using radioactive dye labelling. Local research ethics approval was obtained and the study was submitted to the Integrated Research Application System (IRAS). All data were prospectively collected in our dedicated thoracic surgical database and analyzed at the conclusion of the study. This represents a consecutive series of patients, from January 2016 and until April 2017, who underwent this procedure at our institution: James Cook University Hospital, Middlesbrough, United Kingdom. The primary outcome measured was successful resection rate of the target nodules. RESULTS: Twenty-three patients underwent radiolabeled excision of pulmonary nodules, their average age was 61 years (range, 28-79 years), 13 women and 10 men. The average maximum diameter of the nodule was 8 mm (range, 3-16 mm). All patients underwent successful excision of the target lesion (success rate 100%). One patient (4.3%) sustained pneumothorax following the CT-guided injection of the radio-labelled dye and this required chest drainage prior to general anesthesia. CONCLUSIONS: We conclude that technetium guided pulmonary nodule resection is a very reliable method for localization and resection of subcentimetre nodules which may be otherwise be difficult to identify.
BACKGROUND: Subcentimetre pulmonary nodules can be challenging to locate either during video-assisted thoracoscopic surgery (VATS) or by open techniques. In an era of increasing computed tomography scan availability the number of nodules that are identified that are suspicious for malignancy is rising, and thoracic surgeons require a reliable method to locate these nodules intraoperatively. METHODS: Our aim was to evaluate, for the first time in the UK, resection of pulmonary nodules using radioactive dye labelling. Local research ethics approval was obtained and the study was submitted to the Integrated Research Application System (IRAS). All data were prospectively collected in our dedicated thoracic surgical database and analyzed at the conclusion of the study. This represents a consecutive series of patients, from January 2016 and until April 2017, who underwent this procedure at our institution: James Cook University Hospital, Middlesbrough, United Kingdom. The primary outcome measured was successful resection rate of the target nodules. RESULTS: Twenty-three patients underwent radiolabeled excision of pulmonary nodules, their average age was 61 years (range, 28-79 years), 13 women and 10 men. The average maximum diameter of the nodule was 8 mm (range, 3-16 mm). All patients underwent successful excision of the target lesion (success rate 100%). One patient (4.3%) sustained pneumothorax following the CT-guided injection of the radio-labelled dye and this required chest drainage prior to general anesthesia. CONCLUSIONS: We conclude that technetium guided pulmonary nodule resection is a very reliable method for localization and resection of subcentimetre nodules which may be otherwise be difficult to identify.
Authors: Massimo Bellomi; Giulia Veronesi; Giuseppe Trifirò; Sarah Brambilla; Luke Bonello; Lorenzo Preda; Monica Casiraghi; Alessandro Borri; Giovanni Paganelli; Lorenzo Spaggiari Journal: Ann Thorac Surg Date: 2010-12 Impact factor: 4.330
Authors: Eric L Grogan; David R Jones; Benjamin D Kozower; Winsor D Simmons; Thomas M Daniel Journal: Ann Thorac Surg Date: 2008-02 Impact factor: 4.330
Authors: Brendon M Stiles; Talissa A Altes; David R Jones; K Robert Shen; Gorav Ailawadi; Spencer B Gay; Juan Olazagasti; Patrice K Rehm; Thomas M Daniel Journal: Ann Thorac Surg Date: 2006-10 Impact factor: 4.330
Authors: Franca M A Melfi; Antonio Chella; G Franco Menconi; Francesco Givigliano; Giuseppe Boni; Giuliano Mariani; Paola Sbragia; Carlo Alberto Angeletti Journal: Eur J Cardiothorac Surg Date: 2003-02 Impact factor: 4.191
Authors: Zhen Guo Huang; Cun Li Wang; Hong Liang Sun; Chuan Dong Li; Bao Xiang Gao; He Chen; Min Xing Yang Journal: Korean J Radiol Date: 2021-04-01 Impact factor: 3.500