Literature DB >> 29606308

Single-Cell Transcriptomic Analysis of Tumor Heterogeneity.

Hanna Mendes Levitin1, Jinzhou Yuan1, Peter A Sims2.   

Abstract

Intratumoral heterogeneity is among the greatest challenges in precision cancer therapy. However, developments in high-throughput single-cell RNA sequencing (scRNA-seq) may now provide the statistical power to dissect the diverse cellular populations of tumors. In the future these technologies might inform the selection of targeted combination therapies and enrollment criteria for clinical trials.
Copyright © 2018 Elsevier Inc. All rights reserved.

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Year:  2018        PMID： 29606308      PMCID： PMC5993208          DOI： 10.1016/j.trecan.2018.02.003

Source DB:  PubMed          Journal:  Trends Cancer        ISSN： 2405-8025


  12 in total

1.  Droplet barcoding for single-cell transcriptomics applied to embryonic stem cells.

Authors:  Allon M Klein; Linas Mazutis; Ilke Akartuna; Naren Tallapragada; Adrian Veres; Victor Li; Leonid Peshkin; David A Weitz; Marc W Kirschner
Journal:  Cell       Date:  2015-05-21       Impact factor: 41.582

2.  Highly Parallel Genome-wide Expression Profiling of Individual Cells Using Nanoliter Droplets.

Authors:  Evan Z Macosko; Anindita Basu; Rahul Satija; James Nemesh; Karthik Shekhar; Melissa Goldman; Itay Tirosh; Allison R Bialas; Nolan Kamitaki; Emily M Martersteck; John J Trombetta; David A Weitz; Joshua R Sanes; Alex K Shalek; Aviv Regev; Steven A McCarroll
Journal:  Cell       Date:  2015-05-21       Impact factor: 41.582

3.  Reference component analysis of single-cell transcriptomes elucidates cellular heterogeneity in human colorectal tumors.

Authors:  Huipeng Li; Elise T Courtois; Debarka Sengupta; Yuliana Tan; Kok Hao Chen; Jolene Jie Lin Goh; Say Li Kong; Clarinda Chua; Lim Kiat Hon; Wah Siew Tan; Mark Wong; Paul Jongjoon Choi; Lawrence J K Wee; Axel M Hillmer; Iain Beehuat Tan; Paul Robson; Shyam Prabhakar
Journal:  Nat Genet       Date:  2017-03-20       Impact factor: 38.330

4.  Single-cell in situ RNA profiling by sequential hybridization.

Authors:  Eric Lubeck; Ahmet F Coskun; Timur Zhiyentayev; Mubhij Ahmad; Long Cai
Journal:  Nat Methods       Date:  2014-04       Impact factor: 28.547

5.  RNA imaging. Spatially resolved, highly multiplexed RNA profiling in single cells.

Authors:  Kok Hao Chen; Alistair N Boettiger; Jeffrey R Moffitt; Siyuan Wang; Xiaowei Zhuang
Journal:  Science       Date:  2015-04-09       Impact factor: 47.728

6.  Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma.

Authors:  Anoop P Patel; Itay Tirosh; John J Trombetta; Alex K Shalek; Shawn M Gillespie; Hiroaki Wakimoto; Daniel P Cahill; Brian V Nahed; William T Curry; Robert L Martuza; David N Louis; Orit Rozenblatt-Rosen; Mario L Suvà; Aviv Regev; Bradley E Bernstein
Journal:  Science       Date:  2014-06-12       Impact factor: 47.728

7.  mRNA-Seq whole-transcriptome analysis of a single cell.

Authors:  Fuchou Tang; Catalin Barbacioru; Yangzhou Wang; Ellen Nordman; Clarence Lee; Nanlan Xu; Xiaohui Wang; John Bodeau; Brian B Tuch; Asim Siddiqui; Kaiqin Lao; M Azim Surani
Journal:  Nat Methods       Date:  2009-04-06       Impact factor: 28.547

8.  Massively parallel digital transcriptional profiling of single cells.

Authors:  Grace X Y Zheng; Jessica M Terry; Phillip Belgrader; Paul Ryvkin; Zachary W Bent; Ryan Wilson; Solongo B Ziraldo; Tobias D Wheeler; Geoff P McDermott; Junjie Zhu; Mark T Gregory; Joe Shuga; Luz Montesclaros; Jason G Underwood; Donald A Masquelier; Stefanie Y Nishimura; Michael Schnall-Levin; Paul W Wyatt; Christopher M Hindson; Rajiv Bharadwaj; Alexander Wong; Kevin D Ness; Lan W Beppu; H Joachim Deeg; Christopher McFarland; Keith R Loeb; William J Valente; Nolan G Ericson; Emily A Stevens; Jerald P Radich; Tarjei S Mikkelsen; Benjamin J Hindson; Jason H Bielas
Journal:  Nat Commun       Date:  2017-01-16       Impact factor: 14.919

9.  Seq-Well: portable, low-cost RNA sequencing of single cells at high throughput.

Authors:  Todd M Gierahn; Marc H Wadsworth; Travis K Hughes; Bryan D Bryson; Andrew Butler; Rahul Satija; Sarah Fortune; J Christopher Love; Alex K Shalek
Journal:  Nat Methods       Date:  2017-02-13       Impact factor: 28.547

10.  An Automated Microwell Platform for Large-Scale Single Cell RNA-Seq.

Authors:  Jinzhou Yuan; Peter A Sims
Journal:  Sci Rep       Date:  2016-09-27       Impact factor: 4.379
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  40 in total

Review 1.  Developmental origins and oncogenic pathways in malignant brain tumors.

Authors:  Q Richard Lu; Lily Qian; Xianyao Zhou
Journal:  Wiley Interdiscip Rev Dev Biol       Date:  2019-04-03       Impact factor: 5.814

2.  Automated System for Small-Population Single-Particle Processing Enabled by Exclusive Liquid Repellency.

Authors:  Chao Li; David J Niles; Duane S Juang; Joshua M Lang; David J Beebe
Journal:  SLAS Technol       Date:  2019-06-10       Impact factor: 3.047

Review 3.  Deep Profiling of Cellular Heterogeneity by Emerging Single-Cell Proteomic Technologies.

Authors:  Liwei Yang; Justin George; Jun Wang
Journal:  Proteomics       Date:  2019-12-02       Impact factor: 3.984

4.  Differential Variation Analysis Enables Detection of Tumor Heterogeneity Using Single-Cell RNA-Sequencing Data.

Authors:  Emily F Davis-Marcisak; Thomas D Sherman; Pranay Orugunta; Genevieve L Stein-O'Brien; Sidharth V Puram; Evanthia T Roussos Torres; Alexander C Hopkins; Elizabeth M Jaffee; Alexander V Favorov; Bahman Afsari; Loyal A Goff; Elana J Fertig
Journal:  Cancer Res       Date:  2019-07-23       Impact factor: 12.701

Review 5.  Single Cell Omics of Breast Cancer: An Update on Characterization and Diagnosis.

Authors:  Shailendra Dwivedi; Purvi Purohit; Radhieka Misra; Malavika Lingeswaran; Jeewan Ram Vishnoi; Puneet Pareek; Sanjeev Misra; Praveen Sharma
Journal:  Indian J Clin Biochem       Date:  2019-01-08

Review 6.  A compendium of mutational cancer driver genes.

Authors:  Francisco Martínez-Jiménez; Ferran Muiños; Inés Sentís; Jordi Deu-Pons; Iker Reyes-Salazar; Claudia Arnedo-Pac; Loris Mularoni; Oriol Pich; Jose Bonet; Hanna Kranas; Abel Gonzalez-Perez; Nuria Lopez-Bigas
Journal:  Nat Rev Cancer       Date:  2020-08-10       Impact factor: 60.716

Review 7.  Single-cell RNA sequencing in cardiovascular development, disease and medicine.

Authors:  David T Paik; Sangkyun Cho; Lei Tian; Howard Y Chang; Joseph C Wu
Journal:  Nat Rev Cardiol       Date:  2020-03-30       Impact factor: 32.419

Review 8.  The Spatial and Genomic Hierarchy of Tumor Ecosystems Revealed by Single-Cell Technologies.

Authors:  Eric A Smith; H Courtney Hodges
Journal:  Trends Cancer       Date:  2019-06-18

Review 9.  Cancer biology as revealed by the research autopsy.

Authors:  Christine A Iacobuzio-Donahue; Chelsea Michael; Priscilla Baez; Rajya Kappagantula; Jody E Hooper; Travis J Hollman
Journal:  Nat Rev Cancer       Date:  2019-09-13       Impact factor: 60.716

Review 10.  Orchestrating single-cell analysis with Bioconductor.

Authors:  Robert A Amezquita; Aaron T L Lun; Etienne Becht; Vince J Carey; Lindsay N Carpp; Ludwig Geistlinger; Federico Marini; Kevin Rue-Albrecht; Davide Risso; Charlotte Soneson; Levi Waldron; Hervé Pagès; Mike L Smith; Wolfgang Huber; Martin Morgan; Raphael Gottardo; Stephanie C Hicks
Journal:  Nat Methods       Date:  2019-12-02       Impact factor: 28.547
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