Priscila Berti Zanella1, Camila Coutinho Ávila1, Carolina Guerini de Souza1,2,3. 1. Postgraduate Program in Pulmonary Sciences, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil. 2. Department of Nutrition, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil. 3. Food and Nutrition Research Center, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.
Abstract
BACKGROUND: For patients with pulmonary hypertension, nutrition status is an independent predictor of morbidity and mortality, and energy expenditure can be strongly influenced by lung disease. Indirect calorimetry (IC) is the gold standard for measuring resting energy expenditure (REE), this study aimed to compare the results of REE estimated by different methods with those obtained by IC for patients with pulmonary hypertension. METHODS: In this cross-sectional study (n = 34), REE was estimated by bioelectrical impedance analysis and the predictive equations of Harris-Benedict, Food and Agriculture Organization / World Health Organization, Institute of Medicine, Cunningham, Katch-McArdle, and Mifflin-St Jeor. RESULTS: Mean patient age was 47.0 ± 14.5 years, and 76.5% were women. REE obtained with IC was strongly correlated with all other estimation methods but showed higher mean values: IC 1750.8 ± 434.3 kcal vs bioelectrical impedance analysis, 1549.0 ± 417.8 kcal; Harris-Benedict, 1493.1 ± 337.0 kcal; FAO/WHO, 1536.1 ± 345.0 kcal; Institute of Medicine, 1457.1 ± 293.2 kcal; Cunningham, 1597.3 ± 292.3 kcal; Katch-McArdle, 1447.7 ± 287.0 kcal; and Mifflin-St Jeor, 1388.7 ± 303.9 kcal. The analysis of agreement showed a clinically significant bias of approximately -255 kcal in all estimation methods when compared with IC. CONCLUSION: Although there was a strong correlation between REE estimation methods and IC, there was no agreement between them. All estimation methods underestimated energy needs by about 255 kcal for patients with pulmonary hypertension, and the Cunningham equation had the smallest difference in relation to IC.
BACKGROUND: For patients with pulmonary hypertension, nutrition status is an independent predictor of morbidity and mortality, and energy expenditure can be strongly influenced by lung disease. Indirect calorimetry (IC) is the gold standard for measuring resting energy expenditure (REE), this study aimed to compare the results of REE estimated by different methods with those obtained by IC for patients with pulmonary hypertension. METHODS: In this cross-sectional study (n = 34), REE was estimated by bioelectrical impedance analysis and the predictive equations of Harris-Benedict, Food and Agriculture Organization / World Health Organization, Institute of Medicine, Cunningham, Katch-McArdle, and Mifflin-St Jeor. RESULTS: Mean patient age was 47.0 ± 14.5 years, and 76.5% were women. REE obtained with IC was strongly correlated with all other estimation methods but showed higher mean values: IC 1750.8 ± 434.3 kcal vs bioelectrical impedance analysis, 1549.0 ± 417.8 kcal; Harris-Benedict, 1493.1 ± 337.0 kcal; FAO/WHO, 1536.1 ± 345.0 kcal; Institute of Medicine, 1457.1 ± 293.2 kcal; Cunningham, 1597.3 ± 292.3 kcal; Katch-McArdle, 1447.7 ± 287.0 kcal; and Mifflin-St Jeor, 1388.7 ± 303.9 kcal. The analysis of agreement showed a clinically significant bias of approximately -255 kcal in all estimation methods when compared with IC. CONCLUSION: Although there was a strong correlation between REE estimation methods and IC, there was no agreement between them. All estimation methods underestimated energy needs by about 255 kcal for patients with pulmonary hypertension, and the Cunningham equation had the smallest difference in relation to IC.
Authors: Shaiane Ferreira; Cláudio Augusto Marroni; Jessica Taina Stein; Roberta Rayn; Ana Cristhina Henz; Natália P Schmidt; Randhall B Carteri; Sabrina Alves Fernandes Journal: World J Hepatol Date: 2022-04-27