| Literature DB >> 29589543 |
Atefeh Arab1, Rezvan Yazdian Robati2, Jessica Nicastro3, Roderick Slavcev3,4,5, Javad Behravan1,3,5.
Abstract
Despite years of investigation, breast cancer remains a major cause of death worldwide. Phage display is a powerful molecular method in which peptide and protein libraries can be displayed via genetic fusions on the surface of phages. This approach has tremendous potential for biomedical applications and has already facilitated the discovery of specific antibodies, specific antigens, and peptides with potential roles in the diagnosis and treatment of malignancies including breast cancer. In this review, we discuss the new and the latest advancements in the applications of the phage display technique in the provision of immune therapeutics for breast cancer. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.Entities:
Keywords: Bacteriophage; breast cancer; immune therapeutics; peptide library; phage display; vaccine.
Mesh:
Substances:
Year: 2018 PMID: 29589543 DOI: 10.2174/1381612824666180327152117
Source DB: PubMed Journal: Curr Pharm Des ISSN: 1381-6128 Impact factor: 3.116