Literature DB >> 29589543

Phage-based Nanomedicines as New Immune Therapeutic Agents for Breast Cancer.

Atefeh Arab1, Rezvan Yazdian Robati2, Jessica Nicastro3, Roderick Slavcev3,4,5, Javad Behravan1,3,5.   

Abstract

Despite years of investigation, breast cancer remains a major cause of death worldwide. Phage display is a powerful molecular method in which peptide and protein libraries can be displayed via genetic fusions on the surface of phages. This approach has tremendous potential for biomedical applications and has already facilitated the discovery of specific antibodies, specific antigens, and peptides with potential roles in the diagnosis and treatment of malignancies including breast cancer. In this review, we discuss the new and the latest advancements in the applications of the phage display technique in the provision of immune therapeutics for breast cancer. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

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Keywords:  Bacteriophage; breast cancer; immune therapeutics; peptide library; phage display; vaccine.

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Year:  2018        PMID: 29589543     DOI: 10.2174/1381612824666180327152117

Source DB:  PubMed          Journal:  Curr Pharm Des        ISSN: 1381-6128            Impact factor:   3.116


  2 in total

1.  Screening and identification of a specific peptide binding to breast cancer cells from a phage-displayed peptide library.

Authors:  Huijuan Jin; Xiaojie Gao; Li Xiao; Huimin He; Sinan Cheng; Caixia Zhang; Yifan Hou; Fengying Song; Xiaorong Su; Qian Gao; Zheng Lu; Ruina Yang; Xigui Song; Jin Yang; Wei Duan; Yingchun Hou
Journal:  Biotechnol Lett       Date:  2020-11-03       Impact factor: 2.461

Review 2.  HER2-Positive Breast Cancer Immunotherapy: A Focus on Vaccine Development.

Authors:  Atefeh Arab; Rezvan Yazdian-Robati; Javad Behravan
Journal:  Arch Immunol Ther Exp (Warsz)       Date:  2020-01-09       Impact factor: 4.291

  2 in total

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