Literature DB >> 29588484

Neurosurgical untethering with or without syrinx drainage results in high patient satisfaction and favorable clinical outcome in post-traumatic myelopathy patients.

Ulrika Holmström1, Parmenion P Tsitsopoulos1,2, Hjalmar Flygt1, Anders Holtz1, Niklas Marklund3,4.   

Abstract

STUDY
DESIGN: Retrospective data collection and patient-reported outcome measures.
OBJECTIVES: To investigate surgical outcome, complications, and patient satisfaction in patients with chronic SCI and symptomatic post-traumatic progressive myelopathy (PPM) who underwent neurosurgical untethering and/or spinal cord cyst drainage with the aim of preventing further neurological deterioration.
SETTING: Single-center study at an academic neurosurgery department.
METHODS: All SCI patients who underwent neurosurgery between 1996 and 2013 were retrospectively included. All medical charts and the treating surgeon's operative reports were reviewed to identify surgical indications, surgical technique, and post-operative complications. A questionnaire and an EQ-5D-instrument were used to assess patient's self-described health status and satisfaction at long-term follow-up.
RESULTS: Fifty-two patients (43 men, 9 women) were identified, of whom five were dead and one was lost to follow-up. Main indications for surgery were pain (54%), motor (37%), or sensory (8%) impairment, and spasticity (2.0%). Overall complications were rare (8%). At follow-up, the subjectively perceived outcome was improved in 24 and remained unchanged in 21 patients. Thus, the surgical aim was met in 87% of patients. Of the 46 eligible patients, 38 responded to the questionnaire of whom 65% were satisfied with the surgical results. Patients with cervical lesions were more satisfied with the surgical treatment than patients with thoracic/thoracolumbar lesions (p = 0.05).
CONCLUSIONS: Neurosurgical untethering and/or cyst drainage in chronic SCI patients and PPM resulted in a high degree of patient satisfaction, particularly in cervical SCI patients with minimal complications.

Entities:  

Mesh:

Year:  2018        PMID: 29588484     DOI: 10.1038/s41393-018-0094-y

Source DB:  PubMed          Journal:  Spinal Cord        ISSN: 1362-4393            Impact factor:   2.772


  30 in total

1.  Pathogenesis of post-traumatic syringomyelia.

Authors:  B Williams
Journal:  Br J Neurosurg       Date:  1992       Impact factor: 1.596

2.  Treatment of syringomyelia associated with arachnoid scarring caused by arachnoiditis or trauma.

Authors:  J Klekamp; U Batzdorf; M Samii; H W Bothe
Journal:  J Neurosurg       Date:  1997-02       Impact factor: 5.115

3.  Impact of cordectomy as a treatment option for posttraumatic and non-posttraumatic syringomyelia with tethered cord syndrome and myelopathy.

Authors:  Christian Ewelt; Susanne Stalder; Hans-Jakob Steiger; Gerhard Hildebrandt; Raoul Heilbronner
Journal:  J Neurosurg Spine       Date:  2010-08

4.  Subarachnoid-subarachnoid bypass: a new surgical technique for posttraumatic syringomyelia.

Authors:  Tetsuo Hayashi; Takayoshi Ueta; Masahiro Kubo; Takeshi Maeda; Keiichiro Shiba
Journal:  J Neurosurg Spine       Date:  2013-02-22

5.  A critical appraisal of drainage in syringomyelia.

Authors:  S Sgouros; B Williams
Journal:  J Neurosurg       Date:  1995-01       Impact factor: 5.115

6.  Post-traumatic syringomyelia: the results of surgery.

Authors:  J D Vernon; J R Silver; L Symon
Journal:  Paraplegia       Date:  1983-02

Review 7.  Incidence, prevalence and epidemiology of spinal cord injury: what learns a worldwide literature survey?

Authors:  M Wyndaele; J-J Wyndaele
Journal:  Spinal Cord       Date:  2006-01-03       Impact factor: 2.772

Review 8.  When Pain Hurts: Nociceptive Stimulation Induces a State of Maladaptive Plasticity and Impairs Recovery after Spinal Cord Injury.

Authors:  James W Grau; Yung-Jen Huang; Joel D Turtle; Misty M Strain; Rajesh C Miranda; Sandra M Garraway; Michelle A Hook
Journal:  J Neurotrauma       Date:  2016-12-20       Impact factor: 5.269

9.  Extent of spontaneous motor recovery after traumatic cervical sensorimotor complete spinal cord injury.

Authors:  J D Steeves; J K Kramer; J W Fawcett; J Cragg; D P Lammertse; A R Blight; R J Marino; J F Ditunno; W P Coleman; F H Geisler; J Guest; L Jones; S Burns; M Schubert; H J A van Hedel; A Curt
Journal:  Spinal Cord       Date:  2010-08-17       Impact factor: 2.772

10.  Post-traumatic syringomyelia: outcome predictors.

Authors:  Youssef Karam; Patrick W Hitchon; Nakhle E Mhanna; Wenzhuan He; Jennifer Noeller
Journal:  Clin Neurol Neurosurg       Date:  2014-06-17       Impact factor: 1.876

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  3 in total

1.  Cerebrospinal fluid levels of GFAP and pNF-H are elevated in patients with chronic spinal cord injury and neurological deterioration.

Authors:  Ulrika Holmström; Parmenion P Tsitsopoulos; Anders Holtz; Konstantin Salci; Gerry Shaw; Stefania Mondello; Niklas Marklund
Journal:  Acta Neurochir (Wien)       Date:  2020-06-25       Impact factor: 2.216

2.  Treatment of posttraumatic syringomyelia: evidence from a systematic review.

Authors:  Andrea Kleindienst; Francisco Marin Laut; Verena Roeckelein; Michael Buchfelder; Frank Dodoo-Schittko
Journal:  Acta Neurochir (Wien)       Date:  2020-08-20       Impact factor: 2.216

3.  Long-term outcome following surgical treatment of posttraumatic tethered cord syndrome: a retrospective population-based cohort study.

Authors:  Vasilios Stenimahitis; Alexander Fletcher-Sandersjöö; Charles Tatter; Adrian Elmi-Terander; Erik Edström
Journal:  Spinal Cord       Date:  2022-01-19       Impact factor: 2.473

  3 in total

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