Literature DB >> 20672954

Impact of cordectomy as a treatment option for posttraumatic and non-posttraumatic syringomyelia with tethered cord syndrome and myelopathy.

Christian Ewelt1, Susanne Stalder, Hans-Jakob Steiger, Gerhard Hildebrandt, Raoul Heilbronner.   

Abstract

OBJECT: Spinal cordectomy has recently become more important in the treatment of end-stage posttraumatic or postoperative syringomyelia and arachnopathy as a last resort to manage ascending neurological dysfunction, spasticity, and pain in paraplegic patients. The aim in this study was to confirm a clinical benefit in strict indications for cordectomy.
METHODS: Between February 2000 and September 2007, 15 spinal cordectomies were performed at the Department of Neurosurgery, Cantonal Hospital, St. Gallen. Indications for treatment were end-stage myelopathies caused by syringomyelia, tethered cord syndrome, and arachnopathy with progressive spasticity and pain or progressive upper-level neurological deficits related to the tethered cord syndrome. All patients had severe motor and sensory deficits with no residual voluntary function below the affected level.
RESULTS: Fourteen of 15 patients showed stabilization or even an improvement in motor and sensory function. Four patients suffered from progressive spasticity and 3 from deterioration due to pain. There were no other adverse surgical events.
CONCLUSIONS: Cordectomy can be a useful instrument to preserve functions of the upper extremities and to improve spasticity and pain in patients with severe myelopathy and tethered cord, syringomyelia, or arachnopathy of various etiologies.

Entities:  

Mesh:

Year:  2010        PMID: 20672954     DOI: 10.3171/2010.3.SPINE0976

Source DB:  PubMed          Journal:  J Neurosurg Spine        ISSN: 1547-5646


  3 in total

Review 1.  The leptomeninges as a critical organ for normal CNS development and function: First patient and public involved systematic review of arachnoiditis (chronic meningitis).

Authors:  Carol S Palackdkharry; Stephanie Wottrich; Erin Dienes; Mohamad Bydon; Michael P Steinmetz; Vincent C Traynelis
Journal:  PLoS One       Date:  2022-09-30       Impact factor: 3.752

2.  Neurosurgical untethering with or without syrinx drainage results in high patient satisfaction and favorable clinical outcome in post-traumatic myelopathy patients.

Authors:  Ulrika Holmström; Parmenion P Tsitsopoulos; Hjalmar Flygt; Anders Holtz; Niklas Marklund
Journal:  Spinal Cord       Date:  2018-03-27       Impact factor: 2.772

3.  Treatment of posttraumatic syringomyelia: evidence from a systematic review.

Authors:  Andrea Kleindienst; Francisco Marin Laut; Verena Roeckelein; Michael Buchfelder; Frank Dodoo-Schittko
Journal:  Acta Neurochir (Wien)       Date:  2020-08-20       Impact factor: 2.216

  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.