Literature DB >> 29576924

Arthroscopic Synovectomy Combined with Autologous Fat Grafting in Early Stages of CMC Osteoarthritis of the Thumb.

Robert Kemper1,2, Johanna Wirth2, Eva-Maria Baur2.   

Abstract

Background  Minimal invasive treatments such as arthroscopic techniques may be adequate to restore the anatomy and functional integrity of the thumb CMC (carpometacarpal) joint. In this paper, we reported the interposition of autologous fat tissue in combination with arthroscopic synovectomy/debridement for early stage of the thumb CMC joint osteoarthritis. Patients and Methods  Twelve patients with a mean age of 46 years with early radiological stages of thumb CMC joint osteoarthritis were included. Evaluation of outcome was measured prior and 3, 12, and 24 months after surgery including, Visual Analog Scale (VAS), QuickDASH, grip and pinch strength, range of motion (ROM), and patient satisfaction. Results  Pain at rest (or with load) was reduced from preoperative 4,7 (8,7) to 2 (5,9) at 3 to 6 months; 1,4 (4,3) at 12 months; and 0,75 (2,7) at 2 years after the surgery. Initial preoperative QuickDASH value of 52 points reduced to 33 (17-65) at 6 months, 23 (2-70) at 12 months, and 20 (11-29) at 24 months after the surgery. Grip strength and thumb pinch with respect to the contralateral untreated thumb was reduced in the first 12 months but recovered subsequently. ROM was equal to the contralateral thumb. Three patients suffered from tendinitis and required surgical treatment. One patient indicated prolonged pain symptoms. No infections were noted and no donor-site morbidity or side effects were detected. Conclusion  Arthroscopic synovectomy combined with autologous fat graft is a reliable surgical option for early thumb CMC joint osteoarthritis and that effect continues for more than 24 months.

Entities:  

Keywords:  autologous fat graft; basilar thumb osteoarthrosis; carpometacarpal joint osteoarthrosis; minimal invasive treatment; osteoarthrosis; small joint arthroscopy

Year:  2017        PMID: 29576924      PMCID: PMC5864490          DOI: 10.1055/s-0037-1604045

Source DB:  PubMed          Journal:  J Wrist Surg        ISSN: 2163-3916


  26 in total

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  6 in total

Review 1.  [Minimally invasive procedures in the early stages of trapeziometacarpal joint osteoarthritis : Denervation, arthroscopy and autologous fat transplantation].

Authors:  B Hohendorff; F Neubrech; C K Spies; F Unglaub; L P Müller; C Ries
Journal:  Orthopade       Date:  2022-01-11       Impact factor: 1.087

2.  Development of Autologous Platelet-Rich Plasma Mixed-Microfat as an Advanced Therapy Medicinal Product for Intra-Articular Injection of Radio-Carpal Osteoarthritis: From Validation Data to Preliminary Clinical Results.

Authors:  Alice Mayoly; Aurélie Iniesta; Caroline Curvale; Najib Kachouh; Charlotte Jaloux; Julia Eraud; Marie Vogtensperger; Julie Veran; Fanny Grimaud; Elisabeth Jouve; Dominique Casanova; Florence Sabatier; Régis Legré; Jérémy Magalon
Journal:  Int J Mol Sci       Date:  2019-03-05       Impact factor: 5.923

3.  Autologous Fat Grafting in the Upper Extremity: Defining New Indications.

Authors:  Peter Deptula; Tennyson Block; Kylie Tanabe; David Kulber
Journal:  Plast Reconstr Surg Glob Open       Date:  2022-08-19

4.  Effects of Intra-Articular Autologous Adipose Micrograft for the Treatment of Osteoarthritis in Dogs: A Prospective, Randomized, Controlled Study.

Authors:  Riccardo Botto; Valentina Riccio; Livio Galosi; Giacomo Rossi; Silvia Vincenzetti; Adolfo Maria Tambella; Francesco De Francesco; Luca Pennasilico; Michele Riccio; Alberto Salvaggio; Sara Sassaroli; Angela Palumbo Piccionello
Journal:  Animals (Basel)       Date:  2022-07-20       Impact factor: 3.231

5.  Intra Articular Injection of Autologous Microfat and Platelets-Rich Plasma in the Treatment of Wrist Osteoarthritis: A Pilot Study.

Authors:  Alice Mayoly; Marie Witters; Elisabeth Jouve; Cécilia Bec; Aurélie Iniesta; Najib Kachouh; Julie Veran; Fanny Grimaud; Anouck Coulange Zavarro; Rémi Fernandez; David Bendahan; Laurent Giraudo; Chloé Dumoulin; Christophe Chagnaud; Dominique Casanova; Florence Sabatier; Régis Legré; Charlotte Jaloux; Jérémy Magalon
Journal:  J Clin Med       Date:  2022-09-29       Impact factor: 4.964

Review 6.  Evaluation of Adipose Cell-Based Therapies for the Treatment of Thumb Carpometacarpal Joint Osteoarthritis.

Authors:  Eleni Karagergou; Theodora Ligomenou; Byron Chalidis; Dimitrios Kitridis; Sophia Papadopoulou; Panagiotis Givissis
Journal:  Biomolecules       Date:  2022-03-20
  6 in total

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