| Literature DB >> 2957319 |
P M Hogarth, M L Hibbs, L Bonadonna, B M Scott, E Witort, G A Pietersz, I F McKenzie.
Abstract
A cDNA clone encoding the mouse Ly-17+ Fc receptor for IgG, isolated from a myelomonocytic cell line, was sequenced and expression of mRNA and the functional Fc gamma R investigated. The receptor is a 301 amino acid transmembrane glycoprotein with two homologous extracellular domains that are also homologous to members of the Ig superfamily. The receptor has four sites of N-linked glycosylation and a long 94 amino acid cytoplasmic tail. Northern analysis, immune complex binding, and serological studies demonstrate that the receptor encoded by the cDNA clone binds mouse IgG gamma 1/2b and rabbit IgG complexes.Entities:
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Year: 1987 PMID: 2957319 DOI: 10.1007/bf00365906
Source DB: PubMed Journal: Immunogenetics ISSN: 0093-7711 Impact factor: 2.846