Hyun Woo Goo1. 1. Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, 88, Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, Republic of Korea. ghw68@hanmail.net.
Abstract
BACKGROUND: The effect of cardiac phase on CT pulmonary vascular volumetry is unknown. OBJECTIVE: To evaluate the effect of cardiac phase on CT pulmonary vascular volume ratio in children and young adults with congenital heart disease. MATERIALS AND METHODS: Thirty-one children and young adults (median age 14 years) with congenital heart disease underwent electrocardiography-synchronized cardiothoracic CT at the end-systolic and end-diastolic phases as well as lung perfusion scintigraphy (n=20) or cardiac MRI (n=11). The author calculated right and left pulmonary vascular volumes by using threshold-based CT volumetry. Right pulmonary vascular volume percentages measured by CT obtained at the end-systolic and end-diastolic phases were compared with corresponding values measured by the reference method (lung perfusion scintigraphy or phase-contrast MRI) by using paired t-test and Bland-Altman analysis. RESULTS: The right pulmonary vascular volume percentages measured by CT were significantly greater at the end-systolic phase than at the end-diastolic phase (64.0±14.1% vs. 61.9±10.7%; P<0.01). The end-systolic CT right pulmonary vascular volume percentages were not significantly different from the corresponding values measured by the reference method (64.0±14.1% vs. 65.3±13.6%; P>0.05), while the end-diastolic vascular volume percentages were significantly smaller than the corresponding values measured by the reference method (61.9±10.7% vs. 65.3±13.6%; P=0.01). Bland-Altman analysis showed a mean difference of 1.4±7.2% for the end-systolic CT, which was significantly smaller than that for the end-diastolic CT (3.4±7.0%; P<0.01). CONCLUSION: The CT pulmonary vascular volume ratio is significantly influenced by the cardiac phase of cardiothoracic CT. The end-systolic phase offers more accurate CT pulmonary vascular volumes than the end-diastolic phase.
BACKGROUND: The effect of cardiac phase on CT pulmonary vascular volumetry is unknown. OBJECTIVE: To evaluate the effect of cardiac phase on CT pulmonary vascular volume ratio in children and young adults with congenital heart disease. MATERIALS AND METHODS: Thirty-one children and young adults (median age 14 years) with congenital heart disease underwent electrocardiography-synchronized cardiothoracic CT at the end-systolic and end-diastolic phases as well as lung perfusion scintigraphy (n=20) or cardiac MRI (n=11). The author calculated right and left pulmonary vascular volumes by using threshold-based CT volumetry. Right pulmonary vascular volume percentages measured by CT obtained at the end-systolic and end-diastolic phases were compared with corresponding values measured by the reference method (lung perfusion scintigraphy or phase-contrast MRI) by using paired t-test and Bland-Altman analysis. RESULTS: The right pulmonary vascular volume percentages measured by CT were significantly greater at the end-systolic phase than at the end-diastolic phase (64.0±14.1% vs. 61.9±10.7%; P<0.01). The end-systolic CT right pulmonary vascular volume percentages were not significantly different from the corresponding values measured by the reference method (64.0±14.1% vs. 65.3±13.6%; P>0.05), while the end-diastolic vascular volume percentages were significantly smaller than the corresponding values measured by the reference method (61.9±10.7% vs. 65.3±13.6%; P=0.01). Bland-Altman analysis showed a mean difference of 1.4±7.2% for the end-systolic CT, which was significantly smaller than that for the end-diastolic CT (3.4±7.0%; P<0.01). CONCLUSION: The CT pulmonary vascular volume ratio is significantly influenced by the cardiac phase of cardiothoracic CT. The end-systolic phase offers more accurate CT pulmonary vascular volumes than the end-diastolic phase.
Authors: Peter K T Hui; Hyun Woo Goo; Jing Du; Janice J K Ip; Suzu Kanzaki; Young Jin Kim; Supika Kritsaneepaiboon; Oktavia Lilyasari; Suvipaporn Siripornpitak Journal: Pediatr Radiol Date: 2017-04-24