Literature DB >> 29572640

Quality of life of patients with osteonecrosis of the femoral head: a multicentre study.

Yuko Uesugi1, Takashi Sakai2, Taisuke Seki3, Shinya Hayashi4, Junichi Nakamura5, Yutaka Inaba6, Daisuke Takahashi7, Kan Sasaki8, Goro Motomura9, Naohiko Mashima10, Tamon Kabata11, Akihiro Sudo12, Tetsuya Jinno13, Wataru Ando14, Satoshi Nagoya15, Kengo Yamamoto16, Satoshi Nakasone17, Hiroshi Ito18, Takuaki Yamamoto19, Nobuhiko Sugano20.   

Abstract

PURPOSE: Quality-of-life (QOL) assessments in patients with osteonecrosis of the femoral head (ONFH) have rarely been reported. This multicentre study aimed to elucidate the relationship between disease severity, including necrotic lesion type and radiological staging, and QOL, as well as between patients' characteristics and QOL.
METHODS: Two hundred seventy-four patients with ONFH (108 females, 166 males; median age, 46 years) were asked to complete self-assessment QOL questionnaires including the Japanese Orthopaedic Association Hip Disease Evaluation Questionnaire, Oxford Hip Score, and SF-12v2.
RESULTS: Patients with large necrotic lesion type or collapsed ONFH had low QOL scores. Among patients with non-collapsed lesions, patients with alcohol-associated ONFH had lower QOL scores than those with steroid-associated ONFH, those with bilateral ONFH had lower mental scores, and male patients had worse social condition scores. Among patients with collapsed lesions, middle-aged patients exhibited lower mental QOL, and a strong correlation was observed between social activity and mental health.
CONCLUSION: Collapsed ONFH was associated with low QOL scores. Among patients with non-collapsed lesions, alcohol-associated ONFH, bilateral disease, and male sex were linked to low QOL scores.

Entities:  

Keywords:  Alcohol-associated; Osteonecrosis of the femoral head (ONFH); Quality of life (QOL); Radiological stage; Steroid-associated

Mesh:

Year:  2018        PMID: 29572640     DOI: 10.1007/s00264-018-3897-8

Source DB:  PubMed          Journal:  Int Orthop        ISSN: 0341-2695            Impact factor:   3.075


  23 in total

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