Literature DB >> 29571037

64Cu, a powerful positron emitter for immunoimaging and theranostic: Production via natZnO and natZnO-NPs.

Zahra Karimi1, Mahdi Sadeghi2, Naimeddin Mataji-Kojouri3.   

Abstract

64Cu is one of the most beneficial radionuclide that can be used as a theranostic agent in Positron Emission Tomography (PET) imaging. In this current work, 64Cu was produced with zinc oxide nanoparticles (natZnONPs) and zinc oxide powder (natZnO) via the 64Zn(n,p)64Cu reaction in Tehran Research Reactor (TRR) and the activity values were compared with each other. The theoretical activity of 64Cu also was calculated with MCNPX-2.6 and the cross sections of this reaction were calculated by using TALYS-1.8, EMPIRE-3.2.2 and ALICE/ASH nuclear codes and were compared with experimental values. Transmission Electronic Microscopy (TEM), Scanning Electronic Microscopy (SEM) and X-Ray Diffraction (XRD) analysis were used for samples characterizations. From these results, it's concluded that 64Cu activity value with nanoscale target was achieved more than the bulk state target and had a good adaptation with the MCNPX result.
Copyright © 2018 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  (64)Cu; ALICE/ASH; Activity; EMPIRE-3.2.2; TALYS-1.8; ZnONPs

Mesh:

Substances:

Year:  2018        PMID: 29571037     DOI: 10.1016/j.apradiso.2018.03.007

Source DB:  PubMed          Journal:  Appl Radiat Isot        ISSN: 0969-8043            Impact factor:   1.513


  3 in total

1.  Synthesis and evaluation of 64Cu-radiolabeled NOTA-cetuximab (64Cu-NOTA-C225) for immuno-PET imaging of EGFR expression.

Authors:  Xiaoxia Xu; Teli Liu; Fei Liu; Xiaoyi Guo; Lei Xia; Qing Xie; Nan Li; Haifeng Huang; Xianteng Yang; Yangchun Xin; Hua Zhu; Zhi Yang
Journal:  Chin J Cancer Res       Date:  2019-04       Impact factor: 5.087

2.  Meitner-Auger Electron Emitters for Targeted Radionuclide Therapy: Mercury-197m/g and Antimony-119

Authors:  Parmissa Randhawa; Aeli P Olson; Shaohuang Chen; Kaley Lexi Gower-Fry; Cornelia Hoehr; Jonathan W Engle; Caterina F Ramogida; Valery Radchenko
Journal:  Curr Radiopharm       Date:  2021

Review 3.  64Cu-based Radiopharmaceuticals in Molecular Imaging.

Authors:  Yeye Zhou; Jihui Li; Xin Xu; Man Zhao; Bin Zhang; Shengming Deng; Yiwei Wu
Journal:  Technol Cancer Res Treat       Date:  2019-01-01
  3 in total

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