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Literature DB >> 2955741

Absence of ototoxicity of teichomycin A2 in guinea pigs.

R E Brummett, K E Fox, M Warchol, D Himes.

Abstract

Teichomycin A2 is a new antibiotic that is similar to vancomycin. Because vancomycin is reported to be ototoxic, teichomycin A2 was tested for ototoxicity. No evidence of ototoxicity was found. Furthermore, ethacrynic acid, a diuretic that augments the ototoxicity of many drugs, did not enhance ototoxicity with teichomycin A2.

Entities: Chemical Disease Species

Mesh：

Substances：

Year: 1987 PMID： 2955741 PMCID： PMC174787 DOI： 10.1128/AAC.31.4.612

Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191

11 in total

1. Antibiotic therapy of bacterial endocarditis. VII. Vancomycin for acute micrococcal endocarditis; preliminary report.

Authors: J E GERACI; F R HEILMAN; D R NICHOLS; W E WELLMAN
Journal: Proc Staff Meet Mayo Clin Date: 1958-04-02

2. Interaction of kanamycin and ethacrynic acid. Severe cochlear damage in guinea pigs.

Authors: B A West; R E Brummett; D L Himes
Journal: Arch Otolaryngol Date: 1973-07

3. Comparison of the in vitro activities of teichomycin A2 and vancomycin against staphylococci and enterococci.

Authors: M H Cynamon; P A Granato
Journal: Antimicrob Agents Chemother Date: 1982-03 Impact factor: 5.191

4. Ototoxicity resulting from the combined administration of potent diuretics and other agents.

Authors: R E Brummett
Journal: Scand Audiol Suppl Date: 1981

5. Ototoxicity of tobramycin, gentamicin, amikacin and sisomicin in the guinea pig.

Authors: R E Brummett; K E Fox; T W Bendrick; D L Himes
Journal: J Antimicrob Chemother Date: 1978-05 Impact factor: 5.790

6. Teichomycins, new antibiotics from Actinoplanes teichomyceticus Nov. Sp. I. Description of the producer strain, fermentation studies and biological properties.

Authors: F Parenti; G Beretta; M Berti; V Arioli
Journal: J Antibiot (Tokyo) Date: 1978-04 Impact factor: 2.649

7. Teichomycins, new antibiotics from Actinoplanes teichomyceticus nov. sp. II. Extraction and chemical characterization.

Authors: M R Bardone; M Paternoster; C Coronelli
Journal: J Antibiot (Tokyo) Date: 1978-03 Impact factor: 2.649

Absence of ototoxicity of teichomycin A2 in guinea pigs.

1. Antibiotic therapy of bacterial endocarditis. VII. Vancomycin for acute micrococcal endocarditis; preliminary report.

2. Interaction of kanamycin and ethacrynic acid. Severe cochlear damage in guinea pigs.

3. Comparison of the in vitro activities of teichomycin A2 and vancomycin against staphylococci and enterococci.

4. Ototoxicity resulting from the combined administration of potent diuretics and other agents.

5. Ototoxicity of tobramycin, gentamicin, amikacin and sisomicin in the guinea pig.

6. Teichomycins, new antibiotics from Actinoplanes teichomyceticus Nov. Sp. I. Description of the producer strain, fermentation studies and biological properties.

7. Teichomycins, new antibiotics from Actinoplanes teichomyceticus nov. sp. II. Extraction and chemical characterization.

8. The ototoxic interaction of viomycin, capreomycin and polymyxin B with ethacrynic acid.

9. A comparative study of the ototoxicity of gentamicin and gentamicin C1.

10. Quantitative relationships of the ototoxic interaction of kanamycin and ethacrynic acid.

1. Neurological and Psychiatric Adverse Effects of Antimicrobials.