Literature DB >> 29555805

Aggregation of Markov flows I: theory.

R S MacKay1, J D Robinson2.   

Abstract

A Markov flow is a stationary measure, with the associated flows and mean first passage times, for a continuous-time regular jump homogeneous semi-Markov process on a discrete state space. Nodes in the state space can be eliminated to produce a smaller Markov flow which is a factor of the original one. Some improvements to the elimination methods of Wales are given. The main contribution of the paper is to present an alternative, namely a method to aggregate groups of nodes to produce a factor. The method can be iterated to make hierarchical aggregation schemes. The potential benefits are efficient computation, including recomputation to take into account local changes, and insights into the macroscopic behaviour.This article is part of the theme issue 'Hilbert's sixth problem'.
© 2018 The Author(s).

Keywords:  Markov flow; aggregation methods; clustering; model reduction

Year:  2018        PMID: 29555805      PMCID: PMC5869541          DOI: 10.1098/rsta.2017.0232

Source DB:  PubMed          Journal:  Philos Trans A Math Phys Eng Sci        ISSN: 1364-503X            Impact factor:   4.226


  5 in total

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Authors:  David J Wales
Journal:  J Chem Phys       Date:  2009-05-28       Impact factor: 3.488

3.  Dynamical modeling and analysis of large cellular regulatory networks.

Authors:  D Bérenguier; C Chaouiya; P T Monteiro; A Naldi; E Remy; D Thieffry; L Tichit
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4.  Folding pathways and rates for the three-stranded beta-sheet peptide Beta3s using discrete path sampling.

Authors:  Joanne M Carr; David J Wales
Journal:  J Phys Chem B       Date:  2008-06-28       Impact factor: 2.991

5.  Communication: Analysing kinetic transition networks for rare events.

Authors:  Jacob D Stevenson; David J Wales
Journal:  J Chem Phys       Date:  2014-07-28       Impact factor: 3.488

  5 in total
  3 in total

1.  Hilbert's sixth problem: the endless road to rigour.

Authors:  A N Gorban
Journal:  Philos Trans A Math Phys Eng Sci       Date:  2018-04-28       Impact factor: 4.226

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Journal:  Front Mol Biosci       Date:  2022-01-27

Review 3.  Dynamical Signatures of Multifunnel Energy Landscapes.

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Journal:  J Phys Chem Lett       Date:  2022-07-08       Impact factor: 6.888

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