Eugene C DePasquale1, Abbas Ardehali2. 1. Division of Cardiology. 2. Division of Cardiac Surgery, David Geffen School of Medicine, University of California, Los Angeles, California, USA.
Abstract
PURPOSE OF REVIEW: Primary graft dysfunction (PGD) is common early postheart transplantation; however, use of standardized definitions remains inconsistent. This review focuses on understanding the incidence, classification, risk factors, and management of PGD. RECENT FINDINGS: The incidence and mortality of PGD in heart transplant varies considerably in the published literature ranging from 1.0% to 31% and 3% to 75%, respectively. There is also considerable variation in management strategies with current data favoring early intervention. SUMMARY: PGD in heart transplantation remains a challenging problem associated with significant mortality and morbidity. There is need for a consistent and accessible definition to better define associated risk factors and optimize management strategies.
PURPOSE OF REVIEW: Primary graft dysfunction (PGD) is common early postheart transplantation; however, use of standardized definitions remains inconsistent. This review focuses on understanding the incidence, classification, risk factors, and management of PGD. RECENT FINDINGS: The incidence and mortality of PGD in heart transplant varies considerably in the published literature ranging from 1.0% to 31% and 3% to 75%, respectively. There is also considerable variation in management strategies with current data favoring early intervention. SUMMARY: PGD in heart transplantation remains a challenging problem associated with significant mortality and morbidity. There is need for a consistent and accessible definition to better define associated risk factors and optimize management strategies.
Authors: Moritz Benjamin Immohr; Udo Boeken; Franziska Mueller; Emir Prashovikj; Michiel Morshuis; Charlotte Böttger; Hug Aubin; Jan Gummert; Payam Akhyari; Artur Lichtenberg; René Schramm Journal: ESC Heart Fail Date: 2021-01-21
Authors: S Roest; S E Kaffka Genaamd Dengler; V van Suylen; N P van der Kaaij; K Damman; L W van Laake; J A Bekkers; M Dalinghaus; M E Erasmus; O C Manintveld Journal: Neth Heart J Date: 2020-11-06 Impact factor: 2.380