| Literature DB >> 29553734 |
Yanlong Yang1, Yuting Zhang1,2, Shasha Zhang3, Qingwen Chen4, Ke Ma1,2, Li Bao1,2, Yong Tao3, Wenbing Yin1,2, Guodong Wang4, Hongwei Liu1,2.
Abstract
Sesterterpenes are usually found in plants and fungi, but are rare in bacteria. Here, we present the identification of StsC from Streptomyces somaliensis, a member of the UbiA superfamily, as a membrane-bound sesterterpene cyclase in bacteria. The cyclized products for StsC, somaliensenes A (1) and B (2), were identified by expressing the corresponding gene in an engineered Escherichia coli strain. The structures of 1 and 2 were determined by analysis of the NMR and MS spectroscopic data.Entities:
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Year: 2018 PMID： 29553734 DOI： 10.1021/acs.jnatprod.7b01033
Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050