Literature DB >> 29548470

Characteristics and immune-enhancing activity of pectic polysaccharides from sweet cherry (Prunus avium).

Jinping Cao1, Dandan Tang2, Yue Wang2, Xian Li2, Li Hong3, Chongde Sun4.   

Abstract

Two water soluble polysaccharides components PAPS-1 and PAPS-2 with homogeneously distributed molecular weight were obtained from Prunus avium. PAPS-1 and PAPS-2 contained GalA: Ara: Gal: Rha: GluA: Glu in 49.38: 32.39: 10.68: 4.66: 1.94: 0.48 and 77.18: 14.91: 3.39: 3.46: 0.93: 0.19 M ratios respectively, as well as trace amount of mannose and fucose. Infrared spectroscopy (IR), nuclear magnetic resonance (NMR) and methylation analysis indicated that both fractions were type I rhamnogalacturonan (RG-I) pectic polysaccharides with glycan side chains constituted mainly of arabinose with minor amount of galactose. Galacturonic acid methylation and sugar acetylation was found in both PAPS-1 and PAPS-2. Both PAPS-1 and PAPS-2 significantly induced the NO release from RAW264.7 cells and the expression of several immune-related molecular (TNFα, IL6, IL10, GCSF, iNOS, COX-2) was induced in RAW264.7 cells.
Copyright © 2018 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Characteristics; Immune-enhancing activity; Polysaccharides; Prunus avium

Mesh：

Substances：

Year:  2018        PMID： 29548470     DOI： 10.1016/j.foodchem.2018.01.145

Source DB:  PubMed          Journal:  Food Chem        ISSN： 0308-8146            Impact factor:   7.514


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