Elisavet Moschopoulou1, Iain Hutchison2, Kamaldeep Bhui3, Ania Korszun3. 1. Centre for Psychiatry, Wolfson Institute of Preventive Medicine, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, EC1A 7BE, UK. elisavet.moschopoulou@qmul.ac.uk. 2. Oral and Maxillofacial Surgery, The Royal London Hospital, Barts Health NHS Trust, Whitechapel, London, E1 1BB, UK. 3. Centre for Psychiatry, Wolfson Institute of Preventive Medicine, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, EC1A 7BE, UK.
Abstract
PURPOSE: Head and neck cancer (HNC) diagnosis and treatment are distressing and have immediate detrimental impacts on functioning and quality of life (QoL). Nevertheless, little is known about long-term psychosocial effects. The aim of this study was to determine the prevalence and correlates of clinical post-traumatic stress disorder (PTSD) and subclinical post-traumatic stress symptoms (PTSS) in HNC patients surviving more than 2 years since treatment and in their partners. METHODS: HNC survivors identified from the cancer registry of a London hospital and their partners completed measures of PTSS, depression and anxiety, fear of cancer recurrence, social support, appearance concerns and health-related QoL. Data regarding their clinical and demographic characteristics were also collected. Correlations, as well as linear and logistic regression coefficients, were calculated to estimate associations with PTSS scores. RESULTS: In this analysis of 93 HNC survivors, at a mean of 6 years (SD = 4) after treatment, 33.4% reported PTSS and 11.8% met the criteria for post-traumatic stress disorder (PTSD). Fear of cancer recurrence was independently associated with PTSS (p < .01). In subgroup analyses of patient-partner dyads, 15.4% of patients and 12.8% of partners reported PTSD, with a further 33.3% of patients and 25.7% of partners demonstrating PTSS. Patients' and partners' scores did not differ significantly (p > .05). CONCLUSIONS: This is the first examination of post-traumatic stress in survivors of HNC and shows that high levels of cancer-related PTSS exist for many years after diagnosis in both patients and their partners.
PURPOSE: Head and neck cancer (HNC) diagnosis and treatment are distressing and have immediate detrimental impacts on functioning and quality of life (QoL). Nevertheless, little is known about long-term psychosocial effects. The aim of this study was to determine the prevalence and correlates of clinical post-traumatic stress disorder (PTSD) and subclinical post-traumatic stress symptoms (PTSS) in HNC patients surviving more than 2 years since treatment and in their partners. METHODS: HNC survivors identified from the cancer registry of a London hospital and their partners completed measures of PTSS, depression and anxiety, fear of cancer recurrence, social support, appearance concerns and health-related QoL. Data regarding their clinical and demographic characteristics were also collected. Correlations, as well as linear and logistic regression coefficients, were calculated to estimate associations with PTSS scores. RESULTS: In this analysis of 93 HNC survivors, at a mean of 6 years (SD = 4) after treatment, 33.4% reported PTSS and 11.8% met the criteria for post-traumatic stress disorder (PTSD). Fear of cancer recurrence was independently associated with PTSS (p < .01). In subgroup analyses of patient-partner dyads, 15.4% of patients and 12.8% of partners reported PTSD, with a further 33.3% of patients and 25.7% of partners demonstrating PTSS. Patients' and partners' scores did not differ significantly (p > .05). CONCLUSIONS: This is the first examination of post-traumatic stress in survivors of HNC and shows that high levels of cancer-related PTSS exist for many years after diagnosis in both patients and their partners.
Entities:
Keywords:
Cancer; Caregivers; Head and neck neoplasms; Post-traumatic stress disorder; Survivors
Authors: Pamela H Mitchell; Lynda Powell; James Blumenthal; Jennifer Norten; Gail Ironson; Carol Rogers Pitula; Erika Sivarajan Froelicher; Susan Czajkowski; Marston Youngblood; Marc Huber; Lisa F Berkman Journal: J Cardiopulm Rehabil Date: 2003 Nov-Dec Impact factor: 2.081
Authors: Margaret L Longacre; John A Ridge; Barbara A Burtness; Thomas J Galloway; Carolyn Y Fang Journal: Oral Oncol Date: 2011-12-09 Impact factor: 5.337
Authors: Eric S Zhou; Frank J Penedo; John E Lewis; Mikal Rasheed; Lara Traeger; Suzanne Lechner; Mark Soloway; Bruce R Kava; Michael H Antoni Journal: J Psychosom Res Date: 2010-09-01 Impact factor: 3.006
Authors: Donna M Posluszny; Angela Liegey Dougall; Jonas T Johnson; Athanassios Argiris; Robert L Ferris; Andrew Baum; Dana H Bovbjerg; Mary Amanda Dew Journal: Head Neck Date: 2014-09-17 Impact factor: 3.147
Authors: Sophia K Smith; Sheryl Zimmerman; Christianna S Williams; John S Preisser; Elizabeth C Clipp Journal: J Clin Oncol Date: 2008-02-20 Impact factor: 44.544
Authors: Jacques Ferlay; Isabelle Soerjomataram; Rajesh Dikshit; Sultan Eser; Colin Mathers; Marise Rebelo; Donald Maxwell Parkin; David Forman; Freddie Bray Journal: Int J Cancer Date: 2014-10-09 Impact factor: 7.396
Authors: Mark A Ellis; Katherine R Sterba; Emily A Brennan; Stacey Maurer; Elizabeth G Hill; Terry A Day; Evan M Graboyes Journal: Otolaryngol Head Neck Surg Date: 2019-02-12 Impact factor: 3.497
Authors: Nik Ruzyanei Nik Jaafar; Norhaliza Abd Hamid; Nur Amirah Hamdan; Rama Krsna Rajandram; Raynuha Mahadevan; Mohd Razif Mohamad Yunus; Hazli Zakaria; Noorsuzana Mohd Shariff; Rohayu Hami; Salbiah Isa; Nurul Izzah Shari; Mohammad Farris Iman Leong Bin Abdullah Journal: Front Psychol Date: 2022-06-24
Authors: Natalie G Regier; Aanand D Naik; Elizabeth A Mulligan; Ziad S Nasreddine; Jane A Driver; Yvonne H-F Sada; Jennifer Moye Journal: Psychooncology Date: 2019-06-13 Impact factor: 3.894