BACKGROUND/ OBJECTIVE: This study evaluated the influence of sex on changes in cytokines, heat shock proteins (HSPs), and oxidative stress in response to a single bout of total body resistance exercise. METHODS: Sixteen healthy volunteers (8 men and 8 women), active and recreationally trained in resistance exercise, were subjected to a single bout of total body resistance exercise (3 × 8-10 repetition maximum, 10 exercises, rests periods of 90-120 seconds). Serum creatine kinase (CK), interleukin (IL)-6, IL-10, tumor necrosis factor-α, HSP60, HSP70, thiobarbituric acid reactive substance, and reduced glutathione were assessed at pre-protocol, and 1 hour, 4 hours, and 24 hours post-protocol. RESULTS: Both men and women had a similar increase in CK (p < 0.05) activity at 24 hours post-exercise. Significant sex differences were observed for IL-6. In the men, an increase from baseline was noted at 1 hour for IL-6. In women, an increase from baseline was noted at 4 hours only for IL-6. There was a significant correlation between peak IL-6 blood level and CK level at 24 hours only in the women. No significant changes were observed in IL-10, tumor necrosis factor-α, HSP60, HSP70, thiobarbituric acid reactive substance, and reduced glutathione. CONCLUSION: Acute total body resistance exercise altered circulating levels of IL-6 and sex differences existed in the temporal pattern and magnitude of this response.
BACKGROUND/ OBJECTIVE: This study evaluated the influence of sex on changes in cytokines, heat shock proteins (HSPs), and oxidative stress in response to a single bout of total body resistance exercise. METHODS: Sixteen healthy volunteers (8 men and 8 women), active and recreationally trained in resistance exercise, were subjected to a single bout of total body resistance exercise (3 × 8-10 repetition maximum, 10 exercises, rests periods of 90-120 seconds). Serum creatine kinase (CK), interleukin (IL)-6, IL-10, tumor necrosis factor-α, HSP60, HSP70, thiobarbituric acid reactive substance, and reduced glutathione were assessed at pre-protocol, and 1 hour, 4 hours, and 24 hours post-protocol. RESULTS: Both men and women had a similar increase in CK (p < 0.05) activity at 24 hours post-exercise. Significant sex differences were observed for IL-6. In the men, an increase from baseline was noted at 1 hour for IL-6. In women, an increase from baseline was noted at 4 hours only for IL-6. There was a significant correlation between peak IL-6 blood level and CK level at 24 hours only in the women. No significant changes were observed in IL-10, tumor necrosis factor-α, HSP60, HSP70, thiobarbituric acid reactive substance, and reduced glutathione. CONCLUSION: Acute total body resistance exercise altered circulating levels of IL-6 and sex differences existed in the temporal pattern and magnitude of this response.
Authors: Megan R Wolf; Maren S Fragala; Jeff S Volek; Craig R Denegar; Jeffrey M Anderson; Brett A Comstock; Courtenay Dunn-Lewis; David R Hooper; Tunde K Szivak; Hui-Ying Luk; Carl M Maresh; Keijo Häkkinen; William J Kraemer Journal: Eur J Appl Physiol Date: 2012-01-22 Impact factor: 3.078
Authors: Mikel Izquierdo; Javier Ibañez; Jose A L Calbet; Ion Navarro-Amezqueta; Miriam González-Izal; Fernando Idoate; Keijo Häkkinen; William J Kraemer; Mercedes Palacios-Sarrasqueta; Mar Almar; Esteban M Gorostiaga Journal: Eur J Appl Physiol Date: 2009-08-01 Impact factor: 3.078
Authors: Sílvia Thamilis Barbosa Pessoa Ferreira; Maria do Socorro Brasileiro-Santos; Juliana Baptista Teixeira; Michelle Christiane da Silva Rabello; Virgínia Maria Barros de Lorena; Breno Quintella Farah; Thayse Neves Santos Silva; Anna Myrna Jaguaribe de Lima Journal: Sleep Breath Date: 2021-04-05 Impact factor: 2.816