Literature DB >> 29533776

Glucose Metabolism in Cancer: The Saga of Pyruvate Kinase Continues.

Annamarie E Allen1, Jason W Locasale2.   

Abstract

Altered glucose metabolism is common in cancer. In this issue of Cancer Cell, Morita et al. report new mouse models that express specific isoforms of pyruvate kinase to study glycolysis in tumors. They report several unanticipated findings that challenge current ideas in cancer metabolism.
Copyright © 2018 Elsevier Inc. All rights reserved.

Entities:  

Mesh：

Substances：

Year:  2018        PMID： 29533776      PMCID： PMC6237085          DOI： 10.1016/j.ccell.2018.02.008

Source DB:  PubMed          Journal:  Cancer Cell        ISSN： 1535-6108            Impact factor:   31.743


  10 in total

1.  PKM2 isoform-specific deletion reveals a differential requirement for pyruvate kinase in tumor cells.

Authors:  William J Israelsen; Talya L Dayton; Shawn M Davidson; Brian P Fiske; Aaron M Hosios; Gary Bellinger; Jie Li; Yimin Yu; Mika Sasaki; James W Horner; Laura N Burga; Jianxin Xie; Michael J Jurczak; Ronald A DePinho; Clary B Clish; Tyler Jacks; Richard G Kibbey; Gerburg M Wulf; Dolores Di Vizio; Gordon B Mills; Lewis C Cantley; Matthew G Vander Heiden
Journal:  Cell       Date:  2013-10-10       Impact factor: 41.582

Review 2.  p53: oncogene or anti-oncogene?

Authors:  D P Lane; S Benchimol
Journal:  Genes Dev       Date:  1990-01       Impact factor: 11.361

3.  A Predictive Model for Selective Targeting of the Warburg Effect through GAPDH Inhibition with a Natural Product.

Authors:  Maria V Liberti; Ziwei Dai; Suzanne E Wardell; Joshua A Baccile; Xiaojing Liu; Xia Gao; Robert Baldi; Mahya Mehrmohamadi; Marc O Johnson; Neel S Madhukar; Alexander A Shestov; Iok I Christine Chio; Olivier Elemento; Jeffrey C Rathmell; Frank C Schroeder; Donald P McDonnell; Jason W Locasale
Journal:  Cell Metab       Date:  2017-09-14       Impact factor: 27.287

Review 4.  PKM2, cancer metabolism, and the road ahead.

Authors:  Talya L Dayton; Tyler Jacks; Matthew G Vander Heiden
Journal:  EMBO Rep       Date:  2016-11-17       Impact factor: 8.807

5.  PKM1 Confers Metabolic Advantages and Promotes Cell-Autonomous Tumor Cell Growth.

Authors:  Mami Morita; Taku Sato; Miyuki Nomura; Yoshimi Sakamoto; Yui Inoue; Ryota Tanaka; Shigemi Ito; Koreyuki Kurosawa; Kazunori Yamaguchi; Yuki Sugiura; Hiroshi Takizaki; Yoji Yamashita; Ryuichi Katakura; Ikuro Sato; Masaaki Kawai; Yoshinori Okada; Hitomi Watanabe; Gen Kondoh; Shoko Matsumoto; Ayako Kishimoto; Miki Obata; Masaki Matsumoto; Tatsuro Fukuhara; Hozumi Motohashi; Makoto Suematsu; Masaaki Komatsu; Keiichi I Nakayama; Toshio Watanabe; Tomoyoshi Soga; Hiroshi Shima; Makoto Maemondo; Nobuhiro Tanuma
Journal:  Cancer Cell       Date:  2018-03-12       Impact factor: 31.743

6.  Lost in transition: start-up of glycolysis yields subpopulations of nongrowing cells.

Authors:  Johan H van Heerden; Meike T Wortel; Frank J Bruggeman; Joseph J Heijnen; Yves J M Bollen; Robert Planqué; Josephus Hulshof; Tom G O'Toole; S Aljoscha Wahl; Bas Teusink
Journal:  Science       Date:  2014-01-16       Impact factor: 47.728

7.  Pyruvate kinase isoform expression alters nucleotide synthesis to impact cell proliferation.

Authors:  Sophia Y Lunt; Vinayak Muralidhar; Aaron M Hosios; William J Israelsen; Dan Y Gui; Lauren Newhouse; Martin Ogrodzinski; Vivian Hecht; Kali Xu; Paula N Marín Acevedo; Daniel P Hollern; Gary Bellinger; Talya L Dayton; Stefan Christen; Ilaria Elia; Anh T Dinh; Gregory Stephanopoulos; Scott R Manalis; Michael B Yaffe; Eran R Andrechek; Sarah-Maria Fendt; Matthew G Vander Heiden
Journal:  Mol Cell       Date:  2014-12-04       Impact factor: 17.970

Review 8.  The Warburg Effect: How Does it Benefit Cancer Cells?

Authors:  Maria V Liberti; Jason W Locasale
Journal:  Trends Biochem Sci       Date:  2016-01-05       Impact factor: 13.807

9.  The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth.

Authors:  Heather R Christofk; Matthew G Vander Heiden; Marian H Harris; Arvind Ramanathan; Robert E Gerszten; Ru Wei; Mark D Fleming; Stuart L Schreiber; Lewis C Cantley
Journal:  Nature       Date:  2008-03-13       Impact factor: 49.962

10.  Quantitative determinants of aerobic glycolysis identify flux through the enzyme GAPDH as a limiting step.

Authors:  Alexander A Shestov; Xiaojing Liu; Zheng Ser; Ahmad A Cluntun; Yin P Hung; Lei Huang; Dongsung Kim; Anne Le; Gary Yellen; John G Albeck; Jason W Locasale
Journal:  Elife       Date:  2014-07-09       Impact factor: 8.140
  10 in total
  15 in total

Review 1.  The Role of PKM2 in Metabolic Reprogramming: Insights into the Regulatory Roles of Non-Coding RNAs.

Authors:  Dexter L Puckett; Mohammed Alquraishi; Winyoo Chowanadisai; Ahmed Bettaieb
Journal:  Int J Mol Sci       Date:  2021-01-25       Impact factor: 5.923

2.  Sevoflurane Regulates Glioma Progression by Circ_0002755/miR-628-5p/MAGT1 Axis.

Authors:  Haoyi Li; Tian Xia; Yilin Guan; Yao Yu
Journal:  Cancer Manag Res       Date:  2020-06-30       Impact factor: 3.989

Review 3.  A short review on cross-link between pyruvate kinase (PKM2) and Glioblastoma Multiforme.

Authors:  Harkomal Verma; Ravi P Cholia; Sharanjot Kaur; Monisha Dhiman; Anil K Mantha
Journal:  Metab Brain Dis       Date:  2021-03-02       Impact factor: 3.584

4.  Functional cross-talk between allosteric effects of activating and inhibiting ligands underlies PKM2 regulation.

Authors:  Jamie A Macpherson; Alina Theisen; Laura Masino; Louise Fets; Paul C Driscoll; Vesela Encheva; Ambrosius P Snijders; Stephen R Martin; Jens Kleinjung; Perdita E Barran; Franca Fraternali; Dimitrios Anastasiou
Journal:  Elife       Date:  2019-07-02       Impact factor: 8.713

Review 5.  The Role of PKM2 in Diabetic Microangiopathy.

Authors:  Chao Tu; Liangzhi Wang; Lan Wei
Journal:  Diabetes Metab Syndr Obes       Date:  2022-05-04       Impact factor: 3.249

6.  Crotonylation at serine 46 impairs p53 activity.

Authors:  Peng Liao; Nimisha Bhattarai; Bo Cao; Xiang Zhou; Ji Hoon Jung; Krishna Damera; Taylor T Fuselier; Suresh Thareja; William C Wimley; Binghe Wang; Shelya X Zeng; Hua Lu
Journal:  Biochem Biophys Res Commun       Date:  2020-02-05       Impact factor: 3.322

7.  A new SIRT1 inhibitor, MHY2245, induces autophagy and inhibits energy metabolism via PKM2/mTOR pathway in human ovarian cancer cells.

Authors:  In Hwan Tae; Ji Yeon Son; Su Hyun Lee; Mi-Young Ahn; Kyungsil Yoon; Sungpil Yoon; Hyung Ryong Moon; Hyung Sik Kim
Journal:  Int J Biol Sci       Date:  2020-04-06       Impact factor: 6.580

8.  Nur77-activated lncRNA WFDC21P attenuates hepatocarcinogenesis via modulating glycolysis.

Authors:  Yun-Feng Guan; Qiao-Ling Huang; Yuan-Li Ai; Qi-Tao Chen; Wen-Xiu Zhao; Xiao-Min Wang; Qiao Wu; Hang-Zi Chen
Journal:  Oncogene       Date:  2020-01-20       Impact factor: 9.867

9.  Long non‑coding RNA BCYRN1 promotes glycolysis and tumor progression by regulating the miR‑149/PKM2 axis in non‑small‑cell lung cancer.

Authors:  Ning Lang; Chunyang Wang; Jiangyang Zhao; Feng Shi; Tong Wu; Hongyan Cao
Journal:  Mol Med Rep       Date:  2020-01-16       Impact factor: 2.952

10.  Pyruvate kinase variant of fission yeast tunes carbon metabolism, cell regulation, growth and stress resistance.

Authors:  Stephan Kamrad; Jan Grossbach; Maria Rodríguez-López; Michael Mülleder; StJohn Townsend; Valentina Cappelletti; Gorjan Stojanovski; Clara Correia-Melo; Paola Picotti; Andreas Beyer; Markus Ralser; Jürg Bähler
Journal:  Mol Syst Biol       Date:  2020-04       Impact factor: 13.068
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.