| Literature DB >> 29531862 |
Onofrio Antonio Catalano1,2,3, Vincent Wu2, Umar Mahmood4, Alberto Signore5,3, Mark Vangel6, Andrea Soricelli7, Marco Salvatore8, Debra Gervais2, Bruce R Rosen1.
Abstract
This study investigates the performance of PET/MR versus each sub-modality alone in the assessment of active inflammation in patients with Crohn disease, when compared to surgery as standard of reference. Sensitivity for detecting active inflammation was 91.5% for PET, 80% for MR, and 88% for PET/MR. Specificity for active inflammation was 74% for PET, 87% for MR, and 93% for PET/MR. Diagnostic accuracy was 84% for PET, 83% for MR, and 91% for PET/MR. In conclusion, PET/MR is significantly more accurate than either sub-modality alone and more specific than PET alone in the detection of active inflammation in patients with Crohn disease.Entities:
Keywords: Crohn disease; PET/MR; active inflammation; inflammation
Year: 2018 PMID： 29531862 PMCID： PMC5840324
Source DB: PubMed Journal: Am J Nucl Med Mol Imaging