| Literature DB >> 29528191 |
Maura Massimino1, Douglas B Evans2, Marta Podda1, Claudio Spinelli3, Paola Collini4, Natalia Pizzi5, Archie Bleyer6.
Abstract
In adolescents and young adults, thyroid cancer accounts for 13% of all invasive neoplasms, being three times more frequent in females, but overdiagnosis and overtreatment are common. There are two therapeutic approaches, one radical and no longer preferred in all instances, and the other conservative. Permanent complications of surgery and metabolic irradiation can affect quality of life and carry an economic burden. The overall survival rate approaches 100% for patients with differentiated thyroid cancer regardless of the extent of treatment. Medullary thyroid carcinoma is a very different entity, occurring most frequently in the context of hereditary tumor susceptibility syndromes.Entities:
Keywords: adolescents; overdiagnosis; thyroid cancer; young adults
Mesh:
Year: 2018 PMID: 29528191 DOI: 10.1002/pbc.27025
Source DB: PubMed Journal: Pediatr Blood Cancer ISSN: 1545-5009 Impact factor: 3.167