Literature DB >> 29525884

The Potential of Stem Cells and Stem Cell-Derived Exosomes in Treating Cardiovascular Diseases.

Jing Ni1,2, Yuxi Sun1,2, Zheng Liu3,4.   

Abstract

In recent years, the cardiac protective mechanisms of stem cells have become a research focus. Increasing evidence has suggested that stem cells release vesicles, including exosomes and micro-vesicles. The content of these vesicles relies on an extracellular stimulus, and active ingredients are extensively being studied. Previous studies have confirmed that stem cell-derived exosomes have a cardiac protective function similar to that of stem cells, and promote angiogenesis, decrease apoptosis, and respond to stress. Compared to stem cells, exosomes are more stable without aneuploidy and immune rejection, and may be a promising and effective therapy for cardiovascular diseases. In this review, the biological functions and molecular mechanisms of stem cells and stem cell-derived exosomes are discussed.

Entities:  

Keywords:  Cardiovascular diseases; Exosomes; Stem cells

Mesh：

Year:  2018        PMID： 29525884     DOI： 10.1007/s12265-018-9799-8

Source DB:  PubMed          Journal:  J Cardiovasc Transl Res        ISSN： 1937-5387            Impact factor:   4.132


  111 in total

1.  Heterotopic of bone marrow. Analysis of precursor cells for osteogenic and hematopoietic tissues.

Authors:  A J Friedenstein; K V Petrakova; A I Kurolesova; G P Frolova
Journal:  Transplantation       Date:  1968-03       Impact factor: 4.939

Review 2.  Potential of cardiac stem/progenitor cells and induced pluripotent stem cells for cardiac repair in ischaemic heart disease.

Authors:  Wei Eric Wang; Xiongwen Chen; Steven R Houser; Chunyu Zeng
Journal:  Clin Sci (Lond)       Date:  2013-10       Impact factor: 6.124

3.  Gla-rich protein acts as a calcification inhibitor in the human cardiovascular system.

Authors:  Carla S B Viegas; Marta S Rafael; José L Enriquez; Alexandra Teixeira; Rui Vitorino; Inês M Luís; Rúben M Costa; Sofia Santos; Sofia Cavaco; José Neves; Anjos L Macedo; Brecht A G Willems; Cees Vermeer; Dina C Simes
Journal:  Arterioscler Thromb Vasc Biol       Date:  2014-12-23       Impact factor: 8.311

4.  Exosomes secreted from GATA-4 overexpressing mesenchymal stem cells serve as a reservoir of anti-apoptotic microRNAs for cardioprotection.

Authors:  Bin Yu; Ha Won Kim; Min Gong; Jingcai Wang; Ronald W Millard; Yigang Wang; Muhammad Ashraf; Meifeng Xu
Journal:  Int J Cardiol       Date:  2014-12-23       Impact factor: 4.164

5.  Generation of germline-competent induced pluripotent stem cells.

Authors:  Keisuke Okita; Tomoko Ichisaka; Shinya Yamanaka
Journal:  Nature       Date:  2007-06-06       Impact factor: 49.962

6.  Visualization and in vivo tracking of the exosomes of murine melanoma B16-BL6 cells in mice after intravenous injection.

Authors:  Yuki Takahashi; Makiya Nishikawa; Haruka Shinotsuka; Yuriko Matsui; Saori Ohara; Takafumi Imai; Yoshinobu Takakura
Journal:  J Biotechnol       Date:  2013-04-02       Impact factor: 3.307

7.  Incidence and Expression of Circulating Cell Free p53-Related Genes in Acute Myocardial Infarction Patients.

Authors:  David Pereg; Keren Cohen; Morris Mosseri; Tatiana Berlin; David M Steinberg; Martin Ellis; Osnat Ashur-Fabian
Journal:  J Atheroscler Thromb       Date:  2015-05-11       Impact factor: 4.928

8.  Genesis and growth of extracellular-vesicle-derived microcalcification in atherosclerotic plaques.

Authors:  Joshua D Hutcheson; Claudia Goettsch; Sergio Bertazzo; Natalia Maldonado; Jessica L Ruiz; Wilson Goh; Katsumi Yabusaki; Tyler Faits; Carlijn Bouten; Gregory Franck; Thibaut Quillard; Peter Libby; Masanori Aikawa; Sheldon Weinbaum; Elena Aikawa
Journal:  Nat Mater       Date:  2016-01-11       Impact factor: 43.841

9.  Contribution of bone marrow-derived hematopoietic stem/progenitor cells to the generation of donor-marker⁺ cardiomyocytes in vivo.

Authors:  Mitsuhiro Fukata; Fumihiko Ishikawa; Yuho Najima; Takuji Yamauchi; Yoriko Saito; Katsuto Takenaka; Kohta Miyawaki; Hideki Shimazu; Kazuya Shimoda; Takaaki Kanemaru; Kei-Ichiro Nakamura; Keita Odashiro; Koji Nagafuji; Mine Harada; Koichi Akashi
Journal:  PLoS One       Date:  2013-05-07       Impact factor: 3.240

10.  c-kit+ cells minimally contribute cardiomyocytes to the heart.

Authors:  Jop H van Berlo; Onur Kanisicak; Marjorie Maillet; Ronald J Vagnozzi; Jason Karch; Suh-Chin J Lin; Ryan C Middleton; Eduardo Marbán; Jeffery D Molkentin
Journal:  Nature       Date:  2014-05-07       Impact factor: 49.962
View more
  10 in total

Review 1.  Implications for MicroRNA involvement in the prognosis and treatment of atherosclerosis.

Authors:  Samira Tabaei; Seyyedeh Samaneh Tabaee
Journal:  Mol Cell Biochem       Date:  2021-01-03       Impact factor: 3.396

2.  Exosomes in Cardiovascular Diseases and Treatment: Experimental and Clinical Aspects.

Authors:  Jing Wang; Chenglin Zhao; Junjie Xiao
Journal:  J Cardiovasc Transl Res       Date:  2019-01-07       Impact factor: 4.132

3.  Transplantation of Cardiac Mesenchymal Stem Cell-Derived Exosomes for Angiogenesis.

Authors:  Chengwei Ju; Youngjun Li; Yan Shen; Yutao Liu; Jingwen Cai; Naifeng Liu; Gengshan Ma; Yaoliang Tang
Journal:  J Cardiovasc Transl Res       Date:  2018-10-01       Impact factor: 4.132

Review 4.  The Exosome: a New Player in Diabetic Cardiomyopathy.

Authors:  Lichan Tao; Jia Shi; Xiaoyu Yang; Ling Yang; Fei Hua
Journal:  J Cardiovasc Transl Res       Date:  2018-09-24       Impact factor: 4.132

Review 5.  Immunomodulation by Exosomes in Myocardial Infarction.

Authors:  Wen Pan; Yujiao Zhu; Xiangmin Meng; Chenlin Zhang; Yan Yang; Yihua Bei
Journal:  J Cardiovasc Transl Res       Date:  2018-10-29       Impact factor: 4.132

6.  Transplantation of Cardiac Mesenchymal Stem Cell-Derived Exosomes Promotes Repair in Ischemic Myocardium.

Authors:  Chengwei Ju; Yan Shen; Gengshan Ma; Yutao Liu; Jingwen Cai; Il-Man Kim; Neal L Weintraub; Naifeng Liu; Yaoliang Tang
Journal:  J Cardiovasc Transl Res       Date:  2018-09-19       Impact factor: 4.132

7.  Exosomes derived from pro-inflammatory bone marrow-derived mesenchymal stem cells reduce inflammation and myocardial injury via mediating macrophage polarization.

Authors:  Ruqin Xu; Fangcheng Zhang; Renjie Chai; Wenyi Zhou; Ming Hu; Bin Liu; Xuke Chen; Mingke Liu; Qiong Xu; Ningning Liu; Shiming Liu
Journal:  J Cell Mol Med       Date:  2019-09-26       Impact factor: 5.310

Review 8.  Mesenchymal Stem Cell Exosomes as a New Strategy for the Treatment of Diabetes Complications.

Authors:  Jiachao Xiong; Hao Hu; Rong Guo; Hui Wang; Hua Jiang
Journal:  Front Endocrinol (Lausanne)       Date:  2021-04-29       Impact factor: 5.555

Review 9.  Nanoparticle-Mediated Drug Delivery for the Treatment of Cardiovascular Diseases.

Authors:  Rajasekharreddy Pala; V T Anju; Madhu Dyavaiah; Siddhardha Busi; Surya M Nauli
Journal:  Int J Nanomedicine       Date:  2020-05-27

Review 10.  Recent Advances in the Application of Mesenchymal Stem Cell-Derived Exosomes for Cardiovascular and Neurodegenerative Disease Therapies.

Authors:  Zhimin Yang; Yanyu Li; Zihua Wang
Journal:  Pharmaceutics       Date:  2022-03-11       Impact factor: 6.321
  10 in total

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