Literature DB >> 29523915

[Penile cancer: diagnosis and staging].

K-D Sievert1, D-L Dräger2, F-M Köhn3, S Milerski2, C Protzel4, O W Hakenberg2.   

Abstract

Penile cancer is often an obvious visual diagnosis but histologic verification should be obtained prior to treatment. The clinical examination should determine the tumor stage and whether it has infiltrated the cavernous bodies and/or the urethra and it should adequately assess the inguinal lymph nodes. Preoperative imaging of the lesion is only indicated in equivocal cases. Curative treatment requires the complete removal of the primary tumor and all metastatic lymph nodes. Lymph node management is the key prognostic factor in the treatment of penile cancer. No imagining technique such as the ultrasound, CT, MRI or PET/CT is able to adequately detect micrometastatic lymph nodes. Therefore, invasive (inguinal) lymph node diagnosis is indicated for all tumour stages from pT1G2. Over 90% of penile cancer cases can be cured with early diagnosis and adequate treatment if routine self-examination and physical examinations are regularly performed.

Entities:  

Keywords:  Human papillomavirus; Lymph nodes, ingunal; Metastasis; Phimosis; Squamous cell carcinoma

Mesh:

Year:  2018        PMID: 29523915     DOI: 10.1007/s00120-018-0602-x

Source DB:  PubMed          Journal:  Urologe A        ISSN: 0340-2592            Impact factor:   0.639


  19 in total

1.  The role of magnetic resonance imaging in the local staging of penile cancer.

Authors:  Oliver Kayes; Suks Minhas; Clare Allen; Chris Hare; Alex Freeman; David Ralph
Journal:  Eur Urol       Date:  2006-11-13       Impact factor: 20.096

Review 2.  Functional imaging in penile cancer: PET/computed tomography, MRI, and sentinel lymph node biopsy.

Authors:  Ullrich G Mueller-Lisse; Bernhard Scher; Michael K Scherr; Michael Seitz
Journal:  Curr Opin Urol       Date:  2008-01       Impact factor: 2.309

3.  Sonography: an underutilized diagnostic tool in the assessment of metastatic groin nodes.

Authors:  Ravula Phani Krishna; Sarath Chandra Sistla; Robinson Smile; R Krishnan
Journal:  J Clin Ultrasound       Date:  2008-05       Impact factor: 0.910

4.  [18F]FDG PET/CT for assessing inguinal lymph nodes in patients with penile cancer - correlation with histopathology after inguinal lymphadenectomy.

Authors:  Desiree L Dräger; Martin Heuschkel; Chris Protzel; Andreas Erbersdobler; Bernd J Krause; Oliver W Hakenberg; Sarah M Schwarzenböck
Journal:  Nuklearmedizin       Date:  2018-02-21       Impact factor: 1.379

5.  Detection of inguinal lymph node involvement in penile squamous cell carcinoma by 18F-fluorodeoxyglucose PET/CT: a prospective single-center study.

Authors:  Boris Schlenker; Bernhard Scher; Reinhold Tiling; Sabine Siegert; Edwin Hungerhuber; Christian Gratzke; Derya Tilki; Oliver Reich; Peter Schneede; Peter Bartenstein; Christian G Stief; Michael Seitz
Journal:  Urol Oncol       Date:  2009-12-21       Impact factor: 3.498

6.  Prospective evaluation of (18)F-fluorodeoxyglucose positron emission tomography-computerized tomography to assess inguinal lymph node status in invasive squamous cell carcinoma of the penis.

Authors:  Isabelle Souillac; Jérôme Rigaud; Catherine Ansquer; Louis Marconnet; Olivier Bouchot
Journal:  J Urol       Date:  2011-12-15       Impact factor: 7.450

7.  Factors associated with regional recurrence after lymph node dissection for penile squamous cell carcinoma.

Authors:  Jay P Reddy; Curtis A Pettaway; Lawrence B Levy; Lance C Pagliaro; Pheroze Tamboli; Priya Rao; Isuru Jayaratna; Karen E Hoffman
Journal:  BJU Int       Date:  2016-11-08       Impact factor: 5.588

8.  Prospective evaluation of hybrid 18F-fluorodeoxyglucose positron emission tomography/computed tomography in staging clinically node-negative patients with penile carcinoma.

Authors:  Joost A P Leijte; Niels M Graafland; Renato A Valdés Olmos; Hester H van Boven; Cornelis A Hoefnagel; Simon Horenblas
Journal:  BJU Int       Date:  2009-03-05       Impact factor: 5.588

9.  Squamous cell carcinoma of the penis. III. Treatment of regional lymph nodes.

Authors:  S Horenblas; H van Tinteren; J F Delemarre; L M Moonen; V Lustig; E W van Waardenburg
Journal:  J Urol       Date:  1993-03       Impact factor: 7.450

Review 10.  Lymphadenectomy in the surgical management of penile cancer.

Authors:  Chris Protzel; Antonio Alcaraz; Simon Horenblas; Giorgio Pizzocaro; Alexandre Zlotta; Oliver W Hakenberg
Journal:  Eur Urol       Date:  2009-02-23       Impact factor: 20.096

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  3 in total

1.  The peri- and intratumoral immune cell infiltrate and PD-L1 status in invasive squamous cell carcinomas of the penis.

Authors:  T Müller; M Demes; A Lehn; J Köllermann; S Vallo; P J Wild; R Winkelmann
Journal:  Clin Transl Oncol       Date:  2021-08-27       Impact factor: 3.405

Review 2.  Human papilloma virus: A review study of epidemiology, carcinogenesis, diagnostic methods, and treatment of all HPV-related cancers.

Authors:  Maryam Soheili; Hossein Keyvani; Marzieh Soheili; Sherko Nasseri
Journal:  Med J Islam Repub Iran       Date:  2021-05-22

Review 3.  [175 years of anesthesia and narcosis-Towards a "human right to unconsciousness"].

Authors:  K Lewandowski; B Kretschmer; K W Schmidt
Journal:  Anaesthesist       Date:  2021-09-16       Impact factor: 1.041

  3 in total

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