Background: The 2007 World Cancer Research Fund/American Institute for Cancer Research (WCRF/AICR) guideline provides recommendations for cancer prevention among cancer survivors. Limited data have examined whether guideline adherence is related to health-related quality of life (HRQoL) among Chinese patients with breast cancer. Methods: An ongoing prospective cohort study involving 1,462 Chinese women with early-stage breast cancer assessed exercise, diet, and body mass index (BMI) at baseline and at 18-months follow-up after diagnosis. Each assessment recorded patient habits within the previous 12 months. HRQoL was evaluated by the EORTC Quality of Life Questionnaire-Core 30 (EORTC QLQ-C30). We first compared the level of adherence to WCRF/AICR recommendations before and after cancer diagnosis. We then examined whether adherence to these recommendations after diagnosis was associated with HRQoL at 18 months. Results: The mean adherence score significantly increased from baseline (3.2; SD, 1.1) to 18-month follow-up (3.9; SD, 1.1; P<.001). Overall, increasing adherence to the WCRF/AICR guideline was associated with higher scores of global health status/quality of life (QoL; Ptrend=.011), physical (Ptrend<.001) and role functioning (Ptrend=.024), and lower scores for fatigue (Ptrend=.016), nausea and vomiting (Ptrend<.001), pain (Ptrend=.004), dyspnea (Ptrend=.030), loss of appetite (Ptrend=.007), and diarrhea (Ptrend=.020). Patients with cancer who met the BMI recommendation had higher scores for physical functioning (P=.001) and lower scores for fatigue (P=.024), pain (P<.001), and dyspnea (P=.045). Adherence to physical activity recommendation was associated with better scores of global health status/QoL (P<.001), physical functioning (P=.003), fatigue (P=.002), pain (P=.018), and dyspnea (P=.021). Higher adherence to diet recommendation was associated with lower scores of nausea and vomiting (Ptrend=.005), loss of appetite (Ptrend=.026), constipation (Ptrend=.040), and diarrhea (Ptrend=.031). Conclusions: Chinese patients with breast cancer made positive lifestyle changes early after cancer diagnosis. Increased adherence to WCRF/AICR recommendations after cancer diagnosis may improve HRQoL. Our data suggest that Chinese patients with breast cancer should follow the WCRF/AICR guideline to improve overall well-being.
Background: The 2007 World Cancer Research Fund/American Institute for Cancer Research (WCRF/AICR) guideline provides recommendations for cancer prevention among cancer survivors. Limited data have examined whether guideline adherence is related to health-related quality of life (HRQoL) among Chinese patients with breast cancer. Methods: An ongoing prospective cohort study involving 1,462 Chinese women with early-stage breast cancer assessed exercise, diet, and body mass index (BMI) at baseline and at 18-months follow-up after diagnosis. Each assessment recorded patient habits within the previous 12 months. HRQoL was evaluated by the EORTC Quality of Life Questionnaire-Core 30 (EORTC QLQ-C30). We first compared the level of adherence to WCRF/AICR recommendations before and after cancer diagnosis. We then examined whether adherence to these recommendations after diagnosis was associated with HRQoL at 18 months. Results: The mean adherence score significantly increased from baseline (3.2; SD, 1.1) to 18-month follow-up (3.9; SD, 1.1; P<.001). Overall, increasing adherence to the WCRF/AICR guideline was associated with higher scores of global health status/quality of life (QoL; Ptrend=.011), physical (Ptrend<.001) and role functioning (Ptrend=.024), and lower scores for fatigue (Ptrend=.016), nausea and vomiting (Ptrend<.001), pain (Ptrend=.004), dyspnea (Ptrend=.030), loss of appetite (Ptrend=.007), and diarrhea (Ptrend=.020). Patients with cancer who met the BMI recommendation had higher scores for physical functioning (P=.001) and lower scores for fatigue (P=.024), pain (P<.001), and dyspnea (P=.045). Adherence to physical activity recommendation was associated with better scores of global health status/QoL (P<.001), physical functioning (P=.003), fatigue (P=.002), pain (P=.018), and dyspnea (P=.021). Higher adherence to diet recommendation was associated with lower scores of nausea and vomiting (Ptrend=.005), loss of appetite (Ptrend=.026), constipation (Ptrend=.040), and diarrhea (Ptrend=.031). Conclusions: Chinese patients with breast cancer made positive lifestyle changes early after cancer diagnosis. Increased adherence to WCRF/AICR recommendations after cancer diagnosis may improve HRQoL. Our data suggest that Chinese patients with breast cancer should follow the WCRF/AICR guideline to improve overall well-being.
Authors: Yuan-Yuan Lei; Suzanne C Ho; Thomas K H Lau; Carol Kwok; Ashley Cheng; Ka Li Cheung; Roselle Lee; Winnie Yeo Journal: Qual Life Res Date: 2021-01-14 Impact factor: 4.147
Authors: Merel R van Veen; Floortje Mols; Martijn J L Bours; Matty P Weijenberg; Ellen Kampman; Sandra Beijer Journal: Support Care Cancer Date: 2019-03-29 Impact factor: 3.603
Authors: Evertine Wesselink; Harm van Baar; Moniek van Zutphen; Meilissa Tibosch; Ewout A Kouwenhoven; Eric T P Keulen; Dieuwertje E Kok; Henk K van Halteren; Stephanie O Breukink; Johannes H W de Wilt; Matty P Weijenberg; Marlou-Floor Kenkhuis; Michiel G J Balvers; Renger F Witkamp; Fränzel J B van Duijnhoven; Ellen Kampman; Sandra Beijer; Martijn J L Bours; Renate M Winkels Journal: Cancers (Basel) Date: 2020-12-09 Impact factor: 6.639
Authors: Jennis Freyer-Adam; Florian Noetzel; Sophie Baumann; Ali Alexander Aghdassi; Ulrike Siewert-Markus; Beate Gaertner; Ulrich John Journal: BMC Public Health Date: 2019-11-29 Impact factor: 3.295
Authors: Fernanda S Mazzutti; Isis D D Custódio; Mariana T M Lima; Kamila P de Carvalho; Taísa S S Pereira; Maria Del C B Molina; Paula P L Canto; Carlos E Paiva; Yara C de P Maia Journal: Nutrients Date: 2021-03-29 Impact factor: 5.717
Authors: Yuanyuan Lei; Suzanne C Ho; Carol Kwok; Ashley C Cheng; Ka Li Cheung; Roselle Lee; Winnie Yeo Journal: Cancer Manag Res Date: 2021-06-08 Impact factor: 3.989