| Literature DB >> 29515313 |
Astha Agarwal1, Pranjal Yadava1,2, Krishan Kumar1, Ishwar Singh1, Tanushri Kaul3, Arunava Pattanayak4, Pawan Kumar Agrawal5.
Abstract
Maize is an important crop for billions of people as food, feed, and industrial raw material. It is a prime driver of the global agricultural economy as well as the livelihoods of millions of farmers. Genetic interventions, such as breeding, hybridization and transgenesis have led to increased productivity of this crop in the last 100 years. The technique of genome editing is the latest advancement in genetics. Genome editing can be used for targeted deletions, additions, and corrections in the genome, all aimed at genetic enhancement of crops. The Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/CRISPR associated protein 9 (CRISPR/Cas9) system is a recent genome editing technique that is considered simple, precise, robust and the most revolutionary. This review summarizes the current state of the art and predicts future directions in the use of the CRISPR/Cas9 tool in maize crop improvement.Entities:
Keywords: CRISPR; Cas9; Gene editing; Genome modification; Maize
Year: 2018 PMID: 29515313 PMCID: PMC5834987 DOI: 10.1007/s12298-017-0502-3
Source DB: PubMed Journal: Physiol Mol Biol Plants ISSN: 0974-0430