Literature DB >> 29508607

Divergent Asymmetric Syntheses of Podophyllotoxin and Related Family Members via Stereoselective Reductive Ni-Catalysis.

Jian Xiao1, Xiao-Wei Cong1, Gui-Zhen Yang1, Ya-Wen Wang1,2, Yu Peng1,2.   

Abstract

A nickel-catalyzed reductive cascade approach to the efficient construction of diastereodivergent cores embedded in podophyllum lignans is developed for the first time. Their gram-scale access paved the way for unified syntheses of naturally occurring podophyllotoxin and other members.

Entities:  

Year:  2018        PMID： 29508607     DOI： 10.1021/acs.orglett.8b00408

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  9 in total

1.  Nickel-Catalyzed Dicarbofunctionalization of Alkenes.

Authors:  Xiaoxu Qi; Tianning Diao
Journal:  ACS Catal       Date:  2020-07-02       Impact factor: 13.084

2.  Asymmetric Chemoenzymatic Synthesis of (-)-Podophyllotoxin and Related Aryltetralin Lignans.

Authors:  Jian Li; Xiao Zhang; Hans Renata
Journal:  Angew Chem Int Ed Engl       Date:  2019-07-17       Impact factor: 15.336

Review 3.  Recent strategies and tactics for the enantioselective total syntheses of cyclolignan natural products.

Authors:  Rebekah G Reynolds; Huong Quynh Anh Nguyen; Jordan C T Reddel; Regan J Thomson
Journal:  Nat Prod Rep       Date:  2022-03-23       Impact factor: 13.423

4.  Mechanism of Ni-Catalyzed Reductive 1,2-Dicarbofunctionalization of Alkenes.

Authors:  Qiao Lin; Tianning Diao
Journal:  J Am Chem Soc       Date:  2019-10-28       Impact factor: 15.419

5.  Concise Synthesis of (+)-β- and γ-Apopicropodophyllins, and Dehydrodesoxypodophyllotoxin.

Authors:  Jian Xiao; Guangming Nan; Ya-Wen Wang; Yu Peng
Journal:  Molecules       Date:  2018-11-21       Impact factor: 4.411

6.  Chemoenzymatic Total Synthesis of Deoxy-, epi-, and Podophyllotoxin and a Biocatalytic Kinetic Resolution of Dibenzylbutyrolactones.

Authors:  Mattia Lazzarotto; Lucas Hammerer; Michael Hetmann; Annika Borg; Luca Schmermund; Lorenz Steiner; Peter Hartmann; Ferdinand Belaj; Wolfgang Kroutil; Karl Gruber; Michael Fuchs
Journal:  Angew Chem Int Ed Engl       Date:  2019-05-08       Impact factor: 15.336

7.  Ni-catalysed reductive arylalkylation of unactivated alkenes.

Authors:  Youxiang Jin; Chuan Wang
Journal:  Chem Sci       Date:  2018-12-04       Impact factor: 9.825

8.  Taming the radical cation intermediate enabled one-step access to structurally diverse lignans.

Authors:  Jia-Chen Xiang; Cédric Fung; Qian Wang; Jieping Zhu
Journal:  Nat Commun       Date:  2022-06-16       Impact factor: 17.694

9.  Synthesis of Vicinal Carbocycles by Intramolecular Nickel-Catalyzed Conjunctive Cross-Electrophile Coupling Reaction.

Authors:  Kirsten A Hewitt; Claire A Herbert; Elizabeth R Jarvo
Journal:  Org Lett       Date:  2022-08-04       Impact factor: 6.072
  9 in total

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