Literature DB >> 29508053

[Arthur Vick Prize 2017 of the German Society of Orthopaedic Rheumatology].

L Bause1, A Niemeier2, V Krenn3.   

Abstract

The German Society of Orthopaedic Rheumatology (DGORh) honored Prof. Dr. med. Veit Krenn (MVZ-ZHZMD-Trier) with the Arthur Vick Prize 2017. With this award, scientific results with high impact on the diagnosis, therapy and pathogenetic understanding of rheumatic diseases are honored. In cooperation with pathologists and colleagues from various clinical disciplines Prof. Dr. med. Veit Krenn developed several histopathologic scoring systems which contribute to the diagnosis and pathogenetic understanding of degenerative and rheumatic diseases. These scores include the synovitis score, the meniscal degeneration score, the classification of periprosthetic tissues (SLIM classification), the arthrofibrosis score, the particle score and the CD15 focus score. Of highest relevance for orthopedic rheumatology is the synovitis score which is a semiquantitative score for evaluating immunological and inflammatory changes of synovitis in a graded manner. Based on this score, it is possible to divide results into low-grade synovitis and high-grade synovitis: a synovitis score of 1-4 is called low-grade synovitis and occurs for example in association with osteoarthritis (OA), post-trauma, with meniscal lesions and hemochromatosis. A synovitis score of 5-9 is called high-grade synovitis, e.g. rheumatoid arthritis, psoriatic arthritis, Lyme arthritis, postinfection and reactive arthritis as well as peripheral arthritis with Bechterew's disease (sensitivity 61.7%, specificity 96.1%). The first publication (2002) and an associated subsequent publication (2006) of the synovitis score has led to national and international acceptance of this score as the standard for histopathological assessment of synovitis. The synovitis score provides a diagnostic, standardized and reproducible histopathological evaluation method for joint diseases, particularly when this score is applied in the context with the joint pathology algorithm.

Entities:  

Keywords:  Arthur Vick award; Joint diseases; Joint pathology algorithm; Rheumatoid arthritis; Synovitis-score

Mesh:

Year:  2018        PMID: 29508053     DOI: 10.1007/s00393-018-0433-6

Source DB:  PubMed          Journal:  Z Rheumatol        ISSN: 0340-1855            Impact factor:   1.372


  16 in total

1.  Synovitis score: discrimination between chronic low-grade and high-grade synovitis.

Authors:  V Krenn; L Morawietz; G-R Burmester; R W Kinne; U Mueller-Ladner; B Muller; T Haupl
Journal:  Histopathology       Date:  2006-10       Impact factor: 5.087

2.  Histopathological, immunohistochemical criteria and confocal laser-scanning data of arthrofibrosis.

Authors:  M Ruppert; C Theiss; P Knöß; D Kendoff; M G Krukemeyer; N Schröder; B Brand-Saberi; T Gehrke; V Krenn
Journal:  Pathol Res Pract       Date:  2013-07-17       Impact factor: 3.250

3.  [CD15 focus score for diagnostics of periprosthetic joint infections : Neutrophilic granulocytes quantification mode and the development of morphometric software (CD15 quantifier)].

Authors:  B Kölbel; S Wienert; J Dimitriadis; D Kendoff; T Gehrke; M Huber; L Frommelt; A Tiemann; K Saeger; V Krenn
Journal:  Z Rheumatol       Date:  2015-09       Impact factor: 1.372

Review 4.  Revised histopathological consensus classification of joint implant related pathology.

Authors:  V Krenn; L Morawietz; G Perino; H Kienapfel; R Ascherl; G J Hassenpflug; M Thomsen; P Thomas; M Huber; D Kendoff; D Baumhoer; M G Krukemeyer; S Natu; F Boettner; J Zustin; B Kölbel; W Rüther; J P Kretzer; A Tiemann; A Trampuz; L Frommelt; R Tichilow; S Söder; S Müller; J Parvizi; U Illgner; T Gehrke
Journal:  Pathol Res Pract       Date:  2014-10-17       Impact factor: 3.250

5.  CD15 focus score: Infection diagnosis and stratification into low-virulence and high-virulence microbial pathogens in periprosthetic joint infection.

Authors:  V T Krenn; M Liebisch; B Kölbel; N Renz; T Gehrke; M Huber; M G Krukemeyer; A Trampuz; H Resch; V Krenn
Journal:  Pathol Res Pract       Date:  2017-01-12       Impact factor: 3.250

6.  Prediction of prognosis for prostatic adenocarcinoma by combined histological grading and clinical staging.

Authors:  D F Gleason; G T Mellinger
Journal:  J Urol       Date:  1974-01       Impact factor: 7.450

Review 7.  Immunopathology of synovitis: from histology to molecular pathways.

Authors:  Marleen G van de Sande; Dominique L Baeten
Journal:  Rheumatology (Oxford)       Date:  2015-09-10       Impact factor: 7.580

8.  Quantitative determination of the diagnostic accuracy of the synovitis score and its components.

Authors:  Elisabeth Slansky; Jialiang Li; Thomas Häupl; Lars Morawietz; Veit Krenn; Frank Pessler
Journal:  Histopathology       Date:  2010-09       Impact factor: 5.087

9.  Grading of chronic synovitis--a histopathological grading system for molecular and diagnostic pathology.

Authors:  V Krenn; L Morawietz; T Häupl; J Neidel; I Petersen; A König
Journal:  Pathol Res Pract       Date:  2002       Impact factor: 3.250

10.  Standardisation of labial salivary gland histopathology in clinical trials in primary Sjögren's syndrome.

Authors:  Benjamin A Fisher; Roland Jonsson; Troy Daniels; Michele Bombardieri; Rachel M Brown; Peter Morgan; Stefano Bombardieri; Wan-Fai Ng; Athanasios G Tzioufas; Claudio Vitali; Pepe Shirlaw; Erlin Haacke; Sebastian Costa; Hendrika Bootsma; Valerie Devauchelle-Pensec; Timothy R Radstake; Xavier Mariette; Andrea Richards; Rebecca Stack; Simon J Bowman; Francesca Barone
Journal:  Ann Rheum Dis       Date:  2016-12-13       Impact factor: 19.103

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