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Literature DB >> 2421164

Transfer of specificity by murine alpha and beta T-cell receptor genes.

Z Dembić, W Haas, S Weiss, J McCubrey, H Kiefer, H von Boehmer, M Steinmetz.

Abstract

T-cell receptor alpha- and beta-chain genes were isolated from a class I major histocompatibility complex-restricted cytotoxic T-cell clone and transferred by protoplast fusion into another cytolytic T-cell clone of different specificity. Expression of the transfected alpha and beta genes endowed the recipient cell with the specificity of the donor cell.

Entities: Gene Species

Mesh：

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Year: 1986 PMID： 2421164 DOI： 10.1038/320232a0

Source DB: PubMed Journal: Nature ISSN： 0028-0836 Impact factor: 49.962

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Cited

156 in total

1. Mixed T cell receptor dimers harbor potentially harmful neoreactivity.

Authors: Marleen M van Loenen; Renate de Boer; Avital L Amir; Renate S Hagedoorn; Gerdien L Volbeda; Roelof Willemze; Johannes J van Rood; J H Frederik Falkenburg; Mirjam H M Heemskerk
Journal: Proc Natl Acad Sci U S A Date: 2010-06-01 Impact factor: 11.205

2. Major histocompatibility complex determinants select T-cell receptor alpha chain variable region dominance in a peptide-specific response.

Authors: K Natarajan; D Burstyn; M Zauderer
Journal: Proc Natl Acad Sci U S A Date: 1992-10-01 Impact factor: 11.205

3. Cloning of GT box-binding proteins: a novel Sp1 multigene family regulating T-cell receptor gene expression.

Authors: C Kingsley; A Winoto
Journal: Mol Cell Biol Date: 1992-10 Impact factor: 4.272

Review 4. Role of class I molecules of the major histocompatibility complex in cytotoxic T-cell function in health and disease.

Authors: A J McMichael
Journal: Springer Semin Immunopathol Date: 1992

Transfer of specificity by murine alpha and beta T-cell receptor genes.

1. Mixed T cell receptor dimers harbor potentially harmful neoreactivity.

2. Major histocompatibility complex determinants select T-cell receptor alpha chain variable region dominance in a peptide-specific response.

3. Cloning of GT box-binding proteins: a novel Sp1 multigene family regulating T-cell receptor gene expression.

Review 4. Role of class I molecules of the major histocompatibility complex in cytotoxic T-cell function in health and disease.

Review 5. Structure and function of the T cell antigen receptor.

6. Evolutionary conservation of antigen recognition: the chicken T-cell receptor beta chain.

7. Monosaccharide inhibition of cytotoxic T-cell function: demonstration of clone-specific effects.

8. Expression of T-cell receptor alpha-chain genes in transgenic mice.

Review 9. Immunomodulation in the treatment of haematological malignancies.

10. Local immunosuppressive therapy with monoclonal anti-T cell antibody on renal allograft survival in the rat.