| Literature DB >> 295044 |
E L Prigogina, E W Fleischman, G P Puchkova, O E Kulagina, S A Majakova, S A Balakirev, M A Frenkel, N V Khvatova, I S Peterson.
Abstract
The karyotype of leukemic cells of 78 acute leukemia patients (37 ANLL, 34ALL, and 7 of unknown type) was studied by means of G-banding. Chromosomal abnormalities were found in 50 patients (72%). Chromosomes 8,21,5,7,11, and 19 were preferentially involved in the abnormalities, both in ANLL and in ALL. A high incidence of the characteristic rearrangement t(8;21) was noted in AML: (in 6 of 22 AMP patients). An identical reciprocal translocation--t(4;11)--was seen in 4 out of 34 ALL patients.Entities:
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Year: 1979 PMID： 295044 DOI： 10.1007/bf00289443
Source DB: PubMed Journal: Hum Genet ISSN： 0340-6717 Impact factor: 4.132