Literature DB >> 6573295

Complete or partial trisomy for the long arm of chromosome 1 in patients with various hematologic malignancies.

S E Mamaeva, N N Mamaev, N M Jartseva, L V Belyaeva, E G Scherbakova.   

Abstract

This study contains data obtained from a cytogenetic investigation of six patients with acute and chronic leukaemia. The karyotypes of bone marrow or blood cells of these patients showed a partial or complete trisomy for the long arm of chromosome 1. Three observations revealed a pronounced resistance of cell clones with 1q+ towards cytostatic therapy, and a comparatively short life span of patients after detection of 1q+. The importance of these changes for the role of some chromosomes and chromosome loci in leukaemogenesis is discussed.

Entities:  

Mesh：

Year:  1983        PMID： 6573295     DOI： 10.1007/bf00291527

Source DB:  PubMed          Journal:  Hum Genet        ISSN： 0340-6717            Impact factor:   4.132


  31 in total

1.  Human breast carcinomas: marker chromosomes involving 1q in seven cases.

Authors:  Q V Cruciger; S Pathak; R Cailleau
Journal:  Cytogenet Cell Genet       Date:  1976

2.  Cytogenetic studies in polycythemia vera.

Authors:  D Wurster-Hill; J Whang-Peng; O R McIntyre; L Y Hsu; K Hirschhorn; B Modan; A V Pisciotta; R Pierre; S P Balcerzak; S Murphy; A Weinfeld
Journal:  Semin Hematol       Date:  1976-01       Impact factor: 3.851

3.  Trisomy of 1q in preleukaemia with progression to acute leukaemia.

Authors:  V Najfeld; J V Singer; M C James; P J Fialkow
Journal:  Scand J Haematol       Date:  1978-07

4.  A "Philadelphia-like" chromosome derived from the Y in a patient with refractory dysplastic anemia.

Authors:  D Warburton; A Bluming
Journal:  Blood       Date:  1973-11       Impact factor: 22.113

5.  Cytogenetic studies in non-African Burkitt lymphoma.

Authors:  E C Douglass; I T Magrath; E C Lee; J Whang-Peng
Journal:  Blood       Date:  1980-01       Impact factor: 22.113

6.  Trisomy of the long arm of chromosome No. 1 in human leukemia.

Authors:  M Oshimura; S Sonta; A A Sandberg
Journal:  J Natl Cancer Inst       Date:  1976-01       Impact factor: 13.506

7.  Chromosome 1 in 26 carcinomas of the cervix uteri: structural and numerical changes.

Authors:  N B Atkin; M C Baker
Journal:  Cancer       Date:  1979-08       Impact factor: 6.860

8.  Abnormalities of chromosome No. 1: significance in malignant transformation.

Authors:  J D Rowley
Journal:  Virchows Arch B Cell Pathol       Date:  1978-11-17

9.  Chromosome abnormalities and clinical and morphologic manifestations of chronic myeloid leukemia.

Authors:  E L Prigogina; E W Fleischman; M A Volkova; M A Frenkel
Journal:  Hum Genet       Date:  1978-03-17       Impact factor: 4.132

10.  Detailed cytogenetic study of a metastatic bronchial carcinoma.

Authors:  V J Pickthall
Journal:  Br J Cancer       Date:  1976-09       Impact factor: 7.640
View more
  2 in total

1.  Isochromosome 6p, a unique chromosomal abnormality in retinoblastoma: verification by standard staining techniques, new densitometric methods, and somatic cell hybridization.

Authors:  J Squire; R A Phillips; S Boyce; R Godbout; B Rogers; B L Gallie
Journal:  Hum Genet       Date:  1984       Impact factor: 4.132

2.  Childhood pre-B cell acute lymphoblastic leukemia with translocation t(1;19)(q21.1;p13.3) and two additional chromosomal aberrations involving chromosomes 1, 6, and 13: a case report.

Authors:  Abdulsamad Wafa; Manar As'sad; Thomas Liehr; Abdulmunim Aljapawe; Walid Al Achkar
Journal:  J Med Case Rep       Date:  2017-04-07
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.