Gündüz Durmuş1, Erdal Belen2, Mehmet Mustafa Can2. 1. Department of Cardiology, Haseki Education And Research Hospital, Istanbul, Turkey. Electronic address: drgunduzdurmus@gmail.com. 2. Department of Cardiology, Haseki Education And Research Hospital, Istanbul, Turkey.
Abstract
BACKGROUND: The neutrophil to lymphocyte ratio (NLR), has been proposed as potential indicator of cardiovascular events. Our aim was to determine the relationship between NLR and development of myocardial injury after non-cardiac surgery (MINS). METHODS: This observational cohort study included 255 consecutive noncardiac surgery patients aged ≥45 years. Electrocardiography recordings and high sensitivity cardiac troponin T (hscTnT) levels of the patients were obtained for a period of 3 days postoperatively. RESULTS: MINS was detected in 30 (11.8%) patients using the cut-off level of ≥14 ng/L for hscTnT. In the MINS group NLR (3.79 ± 0.7 vs. 2.69 ± 0.6, p < 0.000) values were higher than non-NLR group. The NLR to be independently associated with the development of MINS (OR: 11.690; CI: 4.619-29.585, p < 0.000). CONCLUSIONS: NLR seems to be a simple, easy and cheap tool to predict the development of MINS in patient undergoing non-cardiac surgery.
BACKGROUND: The neutrophil to lymphocyte ratio (NLR), has been proposed as potential indicator of cardiovascular events. Our aim was to determine the relationship between NLR and development of myocardial injury after non-cardiac surgery (MINS). METHODS: This observational cohort study included 255 consecutive noncardiac surgery patients aged ≥45 years. Electrocardiography recordings and high sensitivity cardiac troponin T (hscTnT) levels of the patients were obtained for a period of 3 days postoperatively. RESULTS: MINS was detected in 30 (11.8%) patients using the cut-off level of ≥14 ng/L for hscTnT. In the MINS group NLR (3.79 ± 0.7 vs. 2.69 ± 0.6, p < 0.000) values were higher than non-NLR group. The NLR to be independently associated with the development of MINS (OR: 11.690; CI: 4.619-29.585, p < 0.000). CONCLUSIONS: NLR seems to be a simple, easy and cheap tool to predict the development of MINS in patient undergoing non-cardiac surgery.
Authors: Jan Larmann; Jessica Handke; Anna S Scholz; Sarah Dehne; Christoph Arens; Hans-Jörg Gillmann; Florian Uhle; Johann Motsch; Markus A Weigand; Henrike Janssen Journal: BMC Cardiovasc Disord Date: 2020-05-18 Impact factor: 2.298