N Reid1, G N Healy2,3,4, J Gianoudis5, M Formica5, P A Gardiner6,7, E E Eakin2, C A Nowson5, R M Daly5,8. 1. School of Public Health, The University of Queensland, Herston Rd, Herston, Brisbane, Queensland, 4006, Australia. n.reid@uq.edu.au. 2. School of Public Health, The University of Queensland, Herston Rd, Herston, Brisbane, Queensland, 4006, Australia. 3. Baker IDI Heart and Diabetes Institute, Melbourne, Australia. 4. School of Physiotherapy, Curtin University, Perth, Australia. 5. Institute for Physical Activity and Nutrition, Deakin University, Geelong, Australia. 6. Centre for Health Services Research, The University of Queensland, Brisbane, Australia. 7. Mater Research Institute, The University of Queensland, South Brisbane, Australia. 8. Department of Medicine, Western Health, The University of Melbourne, Melbourne, Australia.
Abstract
The mechanisms through which excessive sitting time impacts health are important to understand. This study found that each hour of sitting per day was not associated with physical function, although associations with poor body composition were observed. Reducing sitting time for improved weight management in older adults needs further exploration. INTRODUCTION: To examine the association of sitting time and breaks in sitting time with muscle mass, strength, function, and inflammation in older Australians. METHODS: Data from the thigh-worn activPAL3™ monitor (7-day continuous wear) was used to derive time spent sitting (hours) and total number of sit-stand transitions per day. Body composition (dual energy X-ray absorptiometry), lower-body muscle strength, function (timed up-and-go [TUG], 4-m gait speed, four square step test, 30-second sit-to-stand), and serum inflammatory markers (interleukin-[IL-6], IL-8, IL-10, tumor necrosis factor-alpha [TNF-α], and adiponectin) were measured. Multiple regression analyses, adjusted for age, sex, ethnicity, education, employment status, marital status, number of prescription medications, smoking status, vitamin D, and stepping time, were used to assess the associations. RESULTS: Data from 123 community-dwelling older adults (aged 65-84 years, 63% female) were used. Total daily sitting time was associated with lower percentage lean mass (β [95%CI], - 1.70% [- 2.30, - 1.10]) and higher total body fat mass (2.92 kg [1.94, 3.30]). More frequent breaks in sitting time were associated with a 45% reduced risk of having pre-sarcopenia (OR = 0.55; 95% CI 0.34, 0.91; model 1), defined as appendicular lean mass divided by BMI. No significant associations were observed for sitting time or breaks in sitting with measures of muscle strength, function, or inflammation. CONCLUSION: In older community-dwelling adults, greater sitting time was associated with a lower percentage lean mass, while more frequent breaks in sitting time were associated with lower odds of having pre-sarcopenia. This suggests that reducing sedentary time and introducing frequent breaks in sedentary time may be beneficial for improving body composition in healthy older adults.
RCT Entities:
The mechanisms through which excessive sitting time impacts health are important to understand. This study found that each hour of sitting per day was not associated with physical function, although associations with poor body composition were observed. Reducing sitting time for improved weight management in older adults needs further exploration. INTRODUCTION: To examine the association of sitting time and breaks in sitting time with muscle mass, strength, function, and inflammation in older Australians. METHODS: Data from the thigh-worn activPAL3™ monitor (7-day continuous wear) was used to derive time spent sitting (hours) and total number of sit-stand transitions per day. Body composition (dual energy X-ray absorptiometry), lower-body muscle strength, function (timed up-and-go [TUG], 4-m gait speed, four square step test, 30-second sit-to-stand), and serum inflammatory markers (interleukin-[IL-6], IL-8, IL-10, tumor necrosis factor-alpha [TNF-α], and adiponectin) were measured. Multiple regression analyses, adjusted for age, sex, ethnicity, education, employment status, marital status, number of prescription medications, smoking status, vitamin D, and stepping time, were used to assess the associations. RESULTS: Data from 123 community-dwelling older adults (aged 65-84 years, 63% female) were used. Total daily sitting time was associated with lower percentage lean mass (β [95%CI], - 1.70% [- 2.30, - 1.10]) and higher total body fat mass (2.92 kg [1.94, 3.30]). More frequent breaks in sitting time were associated with a 45% reduced risk of having pre-sarcopenia (OR = 0.55; 95% CI 0.34, 0.91; model 1), defined as appendicular lean mass divided by BMI. No significant associations were observed for sitting time or breaks in sitting with measures of muscle strength, function, or inflammation. CONCLUSION: In older community-dwelling adults, greater sitting time was associated with a lower percentage lean mass, while more frequent breaks in sitting time were associated with lower odds of having pre-sarcopenia. This suggests that reducing sedentary time and introducing frequent breaks in sedentary time may be beneficial for improving body composition in healthy older adults.
Entities:
Keywords:
Body composition; Inflammation; Objective measures; Pre-sarcopenia; Sedentary behavior
Authors: Catherine Sherrington; Zoe A Michaleff; Nicola Fairhall; Serene S Paul; Anne Tiedemann; Julie Whitney; Robert G Cumming; Robert D Herbert; Jacqueline C T Close; Stephen R Lord Journal: Br J Sports Med Date: 2016-10-04 Impact factor: 13.800
Authors: Natasha Reid; Robin M Daly; Elisabeth A H Winkler; Paul A Gardiner; Elizabeth G Eakin; Neville Owen; David W Dunstan; Genevieve N Healy Journal: PLoS One Date: 2016-04-13 Impact factor: 3.240
Authors: Jennifer M Blankenship; Elisabeth A H Winkler; Genevieve N Healy; Paddy C Dempsey; John Bellettiere; Neville Owen; David W Dunstan Journal: Med Sci Sports Exerc Date: 2021-12-01 Impact factor: 5.411