Literature DB >> 29474912

Direct Identification of Hundreds of Expression-Modulating Variants using a Multiplexed Reporter Assay.

Ryan Tewhey, Dylan Kotliar, Daniel S Park, Brandon Liu, Sarah Winnicki, Steven K Reilly, Kristian G Andersen, Tarjei S Mikkelsen, Eric S Lander, Stephen F Schaffner, Pardis C Sabeti.   

Abstract

Year:  2018        PMID： 29474912     DOI： 10.1016/j.cell.2018.02.021

Source DB:  PubMed          Journal:  Cell        ISSN： 0092-8674            Impact factor:   41.582


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  16 in total

Review 1.  Towards a comprehensive catalogue of validated and target-linked human enhancers.

Authors:  Molly Gasperini; Jacob M Tome; Jay Shendure
Journal:  Nat Rev Genet       Date:  2020-01-27       Impact factor: 53.242

Review 2.  Integrating natural history collections and comparative genomics to study the genetic architecture of convergent evolution.

Authors:  Sangeet Lamichhaney; Daren C Card; Phil Grayson; João F R Tonini; Gustavo A Bravo; Kathrin Näpflin; Flavia Termignoni-Garcia; Christopher Torres; Frank Burbrink; Julia A Clarke; Timothy B Sackton; Scott V Edwards
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2019-06-03       Impact factor: 6.237

Review 3.  Identifying causal variants and genes using functional genomics in specialized cell types and contexts.

Authors:  Boxiang Liu; Stephen B Montgomery
Journal:  Hum Genet       Date:  2019-07-17       Impact factor: 4.132

4.  Compatibility rules of human enhancer and promoter sequences.

Authors:  Drew T Bergman; Thouis R Jones; Vincent Liu; Judhajeet Ray; Evelyn Jagoda; Layla Siraj; Helen Y Kang; Joseph Nasser; Michael Kane; Antonio Rios; Tung H Nguyen; Sharon R Grossman; Charles P Fulco; Eric S Lander; Jesse M Engreitz
Journal:  Nature       Date:  2022-05-20       Impact factor: 69.504

5.  Functional effects of variation in transcription factor binding highlight long-range gene regulation by epromoters.

Authors:  Joanna Mitchelmore; Nastasiya F Grinberg; Chris Wallace; Mikhail Spivakov
Journal:  Nucleic Acids Res       Date:  2020-04-06       Impact factor: 16.971

6.  Local adaptation and archaic introgression shape global diversity at human structural variant loci.

Authors:  Stephanie M Yan; Rachel M Sherman; Dylan J Taylor; Divya R Nair; Andrew N Bortvin; Michael C Schatz; Rajiv C McCoy
Journal:  Elife       Date:  2021-09-16       Impact factor: 8.140

7.  Functional testing of thousands of osteoarthritis-associated variants for regulatory activity.

Authors:  Jason C Klein; Aidan Keith; Sarah J Rice; Colin Shepherd; Vikram Agarwal; John Loughlin; Jay Shendure
Journal:  Nat Commun       Date:  2019-06-04       Impact factor: 14.919

8.  regBase: whole genome base-wise aggregation and functional prediction for human non-coding regulatory variants.

Authors:  Shijie Zhang; Yukun He; Huanhuan Liu; Haoyu Zhai; Dandan Huang; Xianfu Yi; Xiaobao Dong; Zhao Wang; Ke Zhao; Yao Zhou; Jianhua Wang; Hongcheng Yao; Hang Xu; Zhenglu Yang; Pak Chung Sham; Kexin Chen; Mulin Jun Li
Journal:  Nucleic Acids Res       Date:  2019-12-02       Impact factor: 16.971

9.  Report: NIA workshop on translating genetic variants associated with longevity into drug targets.

Authors:  Nicholas J Schork; Nalini Raghavachari
Journal:  Geroscience       Date:  2018-10-29       Impact factor: 7.713

10.  A systematic evaluation of the design and context dependencies of massively parallel reporter assays.

Authors:  Jason C Klein; Vikram Agarwal; Fumitaka Inoue; Aidan Keith; Beth Martin; Martin Kircher; Nadav Ahituv; Jay Shendure
Journal:  Nat Methods       Date:  2020-10-12       Impact factor: 47.990
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