Literature DB >> 29474326

Transport Time and Preoperating Room Hemostatic Interventions Are Important: Improving Outcomes After Severe Truncal Injury.

John B Holcomb1.   

Abstract

OBJECTIVES: Experience in the ongoing wars in Iraq and Afghanistan confirm that faster transport combined with effective prehospital interventions improves the outcomes of patients suffering hemorrhagic shock. Outcomes of patients with hemorrhagic shock and extremity bleeding have improved with widespread use of tourniquets and early balanced transfusion therapy. Conversely, civilian patients suffering truncal bleeding and shock have the same mortality (46%) over the last 20 years. To understand how to decrease this substantial mortality, one must first critically evaluate all phases of care from point of injury to definitive hemorrhage control in the operating room. DATA SOURCES: Limited literature review. DATA SYNTHESIS: The peak time to death after severe truncal injury is within 30 minutes of injury. However, when adding prehospital transport time, time spent in the emergency department, followed by the time in the operating room, it currently takes 2.1 hours to achieve definitive truncal hemorrhage control. This disparity in uncontrolled truncal bleeding and time to hemorrhage control needs to be reconciled. Prehospital and emergency department whole blood transfusion and temporary truncal hemorrhage control are now possible.
CONCLUSIONS: The importance of rapid transport, early truncal hemorrhage control and whole blood transfusion is now widely recognized. Prehospital temporary truncal hemorrhage control and whole blood transfusion should offer the best possibility of improving patient outcomes after severe truncal injury.

Entities:  

Mesh:

Year:  2018        PMID: 29474326     DOI: 10.1097/CCM.0000000000002915

Source DB:  PubMed          Journal:  Crit Care Med        ISSN: 0090-3493            Impact factor:   7.598


  12 in total

Review 1.  Advanced interventions in the pre-hospital resuscitation of patients with non-compressible haemorrhage after penetrating injuries.

Authors:  E Ter Avest; L Carenzo; R A Lendrum; M D Christian; R M Lyon; C Coniglio; M Rehn; D J Lockey; Z B Perkins
Journal:  Crit Care       Date:  2022-06-20       Impact factor: 19.334

2.  Prehospital synergy: Tranexamic acid and blood transfusion in patients at risk for hemorrhage.

Authors:  Andrew-Paul Deeb; Lara Hoteit; Shimena Li; Francis X Guyette; Brian J Eastridge; Raminder Nirula; Gary A Vercruysse; Terence O'Keeffe; Bellal Joseph; Matthew D Neal; Jason L Sperry; Joshua B Brown
Journal:  J Trauma Acute Care Surg       Date:  2022-04-08       Impact factor: 3.697

3.  Describing the density of high-level trauma centers in the 15 largest US cities.

Authors:  Anne M Stey; Alexandria Byskosh; Caryn Etkin; Robert Mackersie; Deborah M Stein; Karl Y Bilimoria; Marie L Crandall
Journal:  Trauma Surg Acute Care Open       Date:  2020-10-09

4.  'Step Up' approach to the application of REBOA technology in a rural trauma system.

Authors:  Jack P Vernamonti; John Holcomb; Nathan W Mick; Carolyne Falank; Julianne B Ontengco; Joseph Rappold; Forest Raymond Sheppard
Journal:  Trauma Surg Acute Care Open       Date:  2019-07-12

5.  Association of Police Transport With Survival Among Patients With Penetrating Trauma in Philadelphia, Pennsylvania.

Authors:  Eric Winter; Allyson M Hynes; Kaitlyn Shultz; Daniel N Holena; Neil R Malhotra; Jeremy W Cannon
Journal:  JAMA Netw Open       Date:  2021-01-04

Review 6.  Damage control resuscitation: REBOA as the new fourth pillar.

Authors:  Carlos A Ordoñez; Michael W Parra; José Julián Serna; Fernando Rodríguez-Holguin; Alberto García; Alexander Salcedo; Yaset Caicedo; Natalia Padilla; Luis Fernando Pino; Adolfo González Hadad; Mario Alain Herrera; Mauricio Millán; Laureano Quintero-Barrera; Fabian Hernández-Medina; Ricardo Ferrada; Megan Brenner; Todd Rasmussen; Thomas Scalea; Rao Ivatury; John B Holcomb
Journal:  Colomb Med (Cali)       Date:  2020-12-30

7.  Clinical Impact of a Dedicated Trauma Hybrid Operating Room.

Authors:  Tyler J Loftus; Chasen A Croft; Martin D Rosenthal; Alicia M Mohr; Philip A Efron; Frederick A Moore; Gilbert R Upchurch; R Stephen Smith
Journal:  J Am Coll Surg       Date:  2020-11-20       Impact factor: 6.532

8.  Use of bilobed partial resuscitative endovascular balloon occlusion of the aorta is logistically superior in prolonged management of a highly lethal aortic injury.

Authors:  Jevgenia Zilberman-Rudenko; Brandon Behrens; Belinda McCully; Elizabeth N Dewey; Sawyer G Smith; James M Murphy; Andrew Goodman; Samantha J Underwood; Elizabeth A Rick; Brianne M Madtson; Michelle E Thompson; Jacob J Glaser; John B Holcomb; Martin A Schreiber
Journal:  J Trauma Acute Care Surg       Date:  2020-09       Impact factor: 3.697

9.  Intraoperative REBOA: an analysis of the American Association for the Surgery of Trauma AORTA registry.

Authors:  Michael A Vella; Ryan Peter Dumas; Joseph DuBose; Jonathan Morrison; Thomas Scalea; Laura Moore; Jeanette Podbielski; Kenji Inaba; Alice Piccinini; David S Kauvar; Valorie L Baggenstoss; Chance Spalding; Charles Fox; Ernest E Moore; Jeremy W Cannon
Journal:  Trauma Surg Acute Care Open       Date:  2019-11-11

10.  Characteristics of Trauma Mortality in Patients with Aortic Injury in Harris County, Texas.

Authors:  Ronald Chang; Stacy A Drake; John B Holcomb; Garrett Phillips; Charles E Wade; Kristofer M Charlton-Ouw
Journal:  J Clin Med       Date:  2020-09-14       Impact factor: 4.241

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