Literature DB >> 29470190

Blood transfusion management in the severely bleeding military patient.

Jennifer M Gurney1,2, Philip C Spinella2,3.   

Abstract

PURPOSE OF REVIEW: Hemorrhage remains the primary cause of preventable death on the battlefield and in civilian trauma. Hemorrhage control is multifactorial and starts with point-of-injury care. Surgical hemorrhage control and time from injury to surgery is paramount; however, interventions in the prehospital environment and perioperative period affect outcomes. The purpose of this review is to understand concepts and strategies for successful management of the bleeding military patient. Understanding the life-threatening nature of coagulopathy of trauma and implementing strategies aimed at full spectrum hemorrhage management from point of injury to postoperative care will result in improved outcomes in patients with life-threatening bleeding. RECENT
FINDINGS: Timely and appropriate therapies impact survival. Blood product resuscitation for life-threatening hemorrhage should either be with whole blood or a component therapy strategy that recapitulates the functionality of whole blood. The US military has transfused over 10 000 units of whole blood since the beginning of the wars in Iraq and Afghanistan. The well recognized therapeutic benefits of whole blood have pushed this therapy far forward into prehospital care in both US and international military forces. Multiple hemostatic adjuncts are available that are likely beneficial to the bleeding military patient; and other products and techniques are under active investigation.
SUMMARY: Lessons learned in the treatment of combat casualties will likely continue to have positive impact and influence and the management of hemorrhage in the civilian trauma setting.

Entities:  

Mesh:

Year:  2018        PMID: 29470190     DOI: 10.1097/ACO.0000000000000574

Source DB:  PubMed          Journal:  Curr Opin Anaesthesiol        ISSN: 0952-7907            Impact factor:   2.706


  7 in total

1.  Association of Prehospital Plasma Transfusion With Survival in Trauma Patients With Hemorrhagic Shock When Transport Times Are Longer Than 20 Minutes: A Post Hoc Analysis of the PAMPer and COMBAT Clinical Trials.

Authors:  Anthony E Pusateri; Ernest E Moore; Hunter B Moore; Tuan D Le; Francis X Guyette; Michael P Chapman; Angela Sauaia; Arsen Ghasabyan; James Chandler; Kevin McVaney; Joshua B Brown; Brian J Daley; Richard S Miller; Brian G Harbrecht; Jeffrey A Claridge; Herb A Phelan; William R Witham; A Tyler Putnam; Jason L Sperry
Journal:  JAMA Surg       Date:  2020-02-19       Impact factor: 14.766

Review 2.  Histone Deacetylase Inhibitors: A Novel Strategy in Trauma and Sepsis.

Authors:  Aaron M Williams; Isabel S Dennahy; Umar F Bhatti; Ben E Biesterveld; Nathan J Graham; Yongqing Li; Hasan B Alam
Journal:  Shock       Date:  2019-09       Impact factor: 3.454

3.  Life-Threatening Bleeding in Children: A Prospective Observational Study.

Authors:  Julie C Leonard; Cassandra D Josephson; James F Luther; Stephen R Wisniewski; Christine Allen; Fabrizio Chiusolo; Adrienne L Davis; Robert A Finkelstein; Julie C Fitzgerald; Barbara A Gaines; Susan M Goobie; Sheila J Hanson; Hilary A Hewes; Laurie H Johnson; Mark O McCollum; Jennifer A Muszynski; Alison B Nair; Robert B Rosenberg; Thomas M Rouse; Athina Sikavitsas; Marcy N Singleton; Marie E Steiner; Jeffrey S Upperman; Adam M Vogel; Hale Wills; Margaret K Winkler; Philip C Spinella
Journal:  Crit Care Med       Date:  2021-11-01       Impact factor: 9.296

4.  Prehospital administration of blood products: experiences from a Finnish physician-staffed helicopter emergency medical service.

Authors:  Pauli Vuorinen; Joonas-Eemeli Kiili; Piritta Setälä; Antti Kämäräinen; Sanna Hoppu
Journal:  BMC Emerg Med       Date:  2020-07-07

Review 5.  Multiple trauma management in mountain environments - a scoping review : Evidence based guidelines of the International Commission for Mountain Emergency Medicine (ICAR MedCom). Intended for physicians and other advanced life support personnel.

Authors:  G Sumann; D Moens; B Brink; M Brodmann Maeder; M Greene; M Jacob; P Koirala; K Zafren; M Ayala; M Musi; K Oshiro; A Sheets; G Strapazzon; D Macias; P Paal
Journal:  Scand J Trauma Resusc Emerg Med       Date:  2020-12-14       Impact factor: 2.953

6.  Evaluation of a Proportional-Integral-Derivative Controller for Hemorrhage Resuscitation Using a Hardware-in-Loop Test Platform.

Authors:  Eric J Snider; David Berard; Saul J Vega; Guy Avital; Emily N Boice
Journal:  J Pers Med       Date:  2022-06-16

Review 7.  Hypocalcemia as a predictor of mortality and transfusion. A scoping review of hypocalcemia in trauma and hemostatic resuscitation.

Authors:  Shane Kronstedt; Nicholas Roberts; Ricky Ditzel; Justin Elder; Aimee Steen; Kelsey Thompson; Justin Anderson; Jeffrey Siegler
Journal:  Transfusion       Date:  2022-06-24       Impact factor: 3.337

  7 in total

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