Literature DB >> 29469671

Patient perspectives following pharmacogenomics results disclosure in an integrated health system.

Amy A Lemke1, Peter J Hulick1, Dyson T Wake1, Chi Wang2, Annette W Sereika1, Kristen Dilzell Yu1, Nicole S Glaser1, Henry M Dunnenberger1.   

Abstract

AIM: To assess patient perceptions and utilization of pharmacogenomics (PGx) testing in an integrated community health system.
METHODS: Fifty-seven patients completed an online survey assessing their experiences with PGx testing offered through two methods: a designated PGx clinic or direct access in-home testing.
RESULTS: The majority of participants perceived PGx testing as helpful in their healthcare and reported understanding their results. Some had concerns about privacy and discrimination; most lacked familiarity with the Genetic Information Nondiscrimination Act. There were no significant differences in views between participants tested through either model.
CONCLUSION: Participants reported value in both methods of PGx testing. Patient experiences, understanding and result utilization will play an important role in informing future development and implementation of PGx programs.

Entities:  

Keywords:  clinical implementation; patient outcomes; patient perspectives; personalized medicine; pharmacogenomic testing; pharmacogenomics; survey

Mesh:

Year:  2018        PMID: 29469671     DOI: 10.2217/pgs-2017-0191

Source DB:  PubMed          Journal:  Pharmacogenomics        ISSN: 1462-2416            Impact factor:   2.533


  16 in total

1.  Attitudes toward pharmacogenetics in patients undergoing CYP2C19 testing following percutaneous coronary intervention.

Authors:  Grace Lee; Lisa A Varughese; Laura Conway; Carol Stojinski; Sandhya Ashokkumar; Karen Monono; William Matthai; Daniel M Kolansky; Jay Giri; Sony Tuteja
Journal:  Per Med       Date:  2022-01-05       Impact factor: 2.512

Review 2.  Clinical implementation of drug metabolizing gene-based therapeutic interventions worldwide.

Authors:  Evangelia Eirini Tsermpini; Zeina N Al-Mahayri; Bassam R Ali; George P Patrinos
Journal:  Hum Genet       Date:  2021-10-01       Impact factor: 4.132

3.  Concordance between predicted HLA type using next generation sequencing data generated for non-HLA purposes and clinical HLA type.

Authors:  Ann M Moyer; Brian Dukek; Patti Duellman; Brittany Schneider; Laurie Wakefield; Jennifer M Skierka; Rajeswari Avula; Aditya V Bhagwate; Krishna R Kalari; Justin D Kreuter; Matthew P Goetz; Judy C Boughey; John L Black; Manish J Gandhi
Journal:  Hum Immunol       Date:  2020-06-13       Impact factor: 2.850

4.  Adolescent perceptions of pharmacogenetic testing.

Authors:  Stephani L Stancil; Courtney Berrios; Susan Abdel-Rahman
Journal:  Pharmacogenomics       Date:  2021-04-14       Impact factor: 2.533

Review 5.  Moving Pharmacogenetics Into Practice: It's All About the Evidence!

Authors:  Jasmine A Luzum; Natasha Petry; Annette K Taylor; Sara L Van Driest; Henry M Dunnenberger; Larisa H Cavallari
Journal:  Clin Pharmacol Ther       Date:  2021-07-07       Impact factor: 6.903

Review 6.  Pharmacogenomic Clinical Decision Support: A Review, How-to Guide, and Future Vision.

Authors:  Dyson T Wake; D Max Smith; Sadaf Kazi; Henry M Dunnenberger
Journal:  Clin Pharmacol Ther       Date:  2021-08-29       Impact factor: 6.903

7.  Pharmacogenomic (PGx) Counseling: Exploring Participant Questions about PGx Test Results.

Authors:  Tara Schmidlen; Amy C Sturm; Laura B Scheinfeldt
Journal:  J Pers Med       Date:  2020-04-23

8.  Design and Early Implementation Successes and Challenges of a Pharmacogenetics Consult Clinic.

Authors:  Meghan J Arwood; Eric A Dietrich; Benjamin Q Duong; D Max Smith; Kelsey Cook; Amanda Elchynski; Eric I Rosenberg; Katherine N Huber; Ying L Nagoshi; Ashleigh Wright; Jeffrey T Budd; Neal P Holland; Edlira Maska; Danielle Panna; Amanda R Elsey; Larisa H Cavallari; Kristin Wiisanen; Julie A Johnson; John G Gums
Journal:  J Clin Med       Date:  2020-07-17       Impact factor: 4.241

9.  Patient-Reported Outcomes and Experiences with Population Genetic Testing Offered Through a Primary Care Network.

Authors:  Amy A Lemke; Laura M Amendola; Jennifer Thompson; Henry M Dunnenberger; Kristine Kuchta; Chi Wang; Kristen Dilzell-Yu; Peter J Hulick
Journal:  Genet Test Mol Biomarkers       Date:  2021-02

Review 10.  Pharmacogenomics cascade testing (PhaCT): a novel approach for preemptive pharmacogenomics testing to optimize medication therapy.

Authors:  Don Roosan; Angela Hwang; Moom R Roosan
Journal:  Pharmacogenomics J       Date:  2020-08-25       Impact factor: 3.550

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