Hamed Mohammadi1, Ahmad Jayedi2, Ehsan Ghaedi3, Danial Golbidi4, Sakineh Shab-Bidar5. 1. Department of Community Nutrition, School of Nutrition and Food Science, Isfahan University of Medical Sciences, Isfahan, Iran. Electronic address: mohamadihd@gmail.com. 2. Department of Community Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran. Electronic address: ahmadjayedi@yahoo.com. 3. Cancer, Environmental and Petroleum Pollutant Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran. Electronic address: En7cyrus@gmail.com. 4. Isfahan University of Medical Sciences, Isfahan, Iran. Electronic address: Golbidi@gmail.com. 5. Department of Community Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran. Electronic address: s_shabbidar@tums.ac.ir.
Abstract
BACKGROUND & AIMS: We performed a meta-analysis to illuminate and quantify the potential relationship between poultry intake and risk of stroke through summarizing available evidence using a dose-response meta-analysis of prospective cohort studies. METHODS: Pertinent prospective cohort studies attained using electronic searches through PubMed, and Scopus up to September 25th, 2017. Relative risks (RR) s with corresponding 95% confidence intervals (CIs) of the highest versus the lowest for cohort studies were evaluated using DerSimonian and Laird random-effects models to find combined RRs. We also assessed the dose-response effect of this relationship. RESULTS: A total of 7 studies involving 354 718 participants were met inclusion criteria. The pooled RR of total stroke risk was [RR = 0.92 95% CI, 0.82, 1.03, I2 = 19.8%, Pheterogeneity = 0.28] for the highest versus lowest categories of poultry intake. Subgroup analysis showed an inverse associations for the US people [RR = 0.86 95% CI, 0.77, 0.95, I2 = 0.0%, Pheterogeneity = 0.38] and women [RR = 0.83, 95% CI, 0.72, 0.93, I2 = 0.0%, Pheterogeneity = 0.63]. We did not obtain any significant association in the subtypes of strokes with highest versus lowest poultry intake [Ischemic stroke (RR = 0.91; 95% CI: 0.79, 1.02, I2 = 0.0%, p = 0.93), Hemorrhagic (RR = 0.82; 95% CI: 0.59, 1.04, I2 = 20.5%, Pheterogeneity = 0.28)]. One serving per week increment in poultry intake was not associated with the risk of stroke (RR: 1.00, 95% CI: 0.96, 1.03, I2 = 69.0%, Pheterogeneity = 0.004). Nonlinear dose-response meta-analysis showed lower risk of stroke at consumption ∼1 serving/week. CONCLUSION: Our meta-analysis revealed that poultry intake is not associated with total stroke risk; furthermore, an inverse relationship in US population and females must be interpreted with caution.
BACKGROUND & AIMS: We performed a meta-analysis to illuminate and quantify the potential relationship between poultry intake and risk of stroke through summarizing available evidence using a dose-response meta-analysis of prospective cohort studies. METHODS: Pertinent prospective cohort studies attained using electronic searches through PubMed, and Scopus up to September 25th, 2017. Relative risks (RR) s with corresponding 95% confidence intervals (CIs) of the highest versus the lowest for cohort studies were evaluated using DerSimonian and Laird random-effects models to find combined RRs. We also assessed the dose-response effect of this relationship. RESULTS: A total of 7 studies involving 354 718 participants were met inclusion criteria. The pooled RR of total stroke risk was [RR = 0.92 95% CI, 0.82, 1.03, I2 = 19.8%, Pheterogeneity = 0.28] for the highest versus lowest categories of poultry intake. Subgroup analysis showed an inverse associations for the US people [RR = 0.86 95% CI, 0.77, 0.95, I2 = 0.0%, Pheterogeneity = 0.38] and women [RR = 0.83, 95% CI, 0.72, 0.93, I2 = 0.0%, Pheterogeneity = 0.63]. We did not obtain any significant association in the subtypes of strokes with highest versus lowest poultry intake [Ischemic stroke (RR = 0.91; 95% CI: 0.79, 1.02, I2 = 0.0%, p = 0.93), Hemorrhagic (RR = 0.82; 95% CI: 0.59, 1.04, I2 = 20.5%, Pheterogeneity = 0.28)]. One serving per week increment in poultry intake was not associated with the risk of stroke (RR: 1.00, 95% CI: 0.96, 1.03, I2 = 69.0%, Pheterogeneity = 0.004). Nonlinear dose-response meta-analysis showed lower risk of stroke at consumption ∼1 serving/week. CONCLUSION: Our meta-analysis revealed that poultry intake is not associated with total stroke risk; furthermore, an inverse relationship in US population and females must be interpreted with caution.
Authors: Keren Papier; Georgina K Fensom; Anika Knuppel; Paul N Appleby; Tammy Y N Tong; Julie A Schmidt; Ruth C Travis; Timothy J Key; Aurora Perez-Cornago Journal: BMC Med Date: 2021-03-02 Impact factor: 8.775
Authors: Tammy Y N Tong; Paul N Appleby; Timothy J Key; Christina C Dahm; Kim Overvad; Anja Olsen; Anne Tjønneland; Verena Katzke; Tilman Kühn; Heiner Boeing; Anna Karakatsani; Eleni Peppa; Antonia Trichopoulou; Elisabete Weiderpass; Giovanna Masala; Sara Grioni; Salvatore Panico; Rosario Tumino; Jolanda M A Boer; W M Monique Verschuren; J Ramón Quirós; Antonio Agudo; Miguel Rodríguez-Barranco; Liher Imaz; María-Dolores Chirlaque; Conchi Moreno-Iribas; Gunnar Engström; Emily Sonestedt; Marcus Lind; Julia Otten; Kay-Tee Khaw; Dagfinn Aune; Elio Riboli; Nicholas J Wareham; Fumiaki Imamura; Nita G Forouhi; Emanuele di Angelantonio; Angela M Wood; Adam S Butterworth; Aurora Perez-Cornago Journal: Eur Heart J Date: 2020-07-21 Impact factor: 35.855