| Literature DB >> 29458779 |
I M E Desar1, P B Ottevanger1, C Benson2, W T A van der Graaf3.
Abstract
Uterine sarcomas (US) are rare mesenchymal tumours of the uterus and are divided mainly into uterine leiomyosarcoma (uLMS), low grade endometrial stromal sarcoma (LG-ESS), high grade endometrial stromal sarcoma (HG-ESS), adenosarcomas and high grade undifferentiated sarcoma (HGUS). US are often high-grade tumours with a high local recurrence rate and metastatic risk. We here discuss the current standard of care and knowledge of systemic therapy for adult uterine sarcomas, in particular uLMS, LG-ESS, HG-ESS and HGUS, in both the adjuvant as well as the metastatic setting.Entities:
Keywords: Chemotherapy; Hormone therapy; Systemic treatment; Targeted therapy; Uterine sarcoma
Mesh:
Year: 2017 PMID: 29458779 DOI: 10.1016/j.critrevonc.2017.12.009
Source DB: PubMed Journal: Crit Rev Oncol Hematol ISSN: 1040-8428 Impact factor: 6.312