Literature DB >> 29441283

Caspofungin resistant disseminated candidiasis in a 7-year-old girl with T cell lymphoma: a case report.

Michael Schmalz1, Manasa Joysula1, Jack H Staddon1, Arthur Feinberg1.   

Abstract

Immunocompromised patients are at increased risk of disseminated candidiasis. Guidelines for the treatment of invasive candidiasis were last published in 2009, but resistance to the recommended treatment has recently been described in the literature. Here we present the case of an immunocompromised child with T-cell lymphoma who died secondary to disseminated candidiasis despite prolonged antifungal therapy. Awareness of the increasing resistance patterns of Candida when caring for immunocompromised patients, especially pediatric patients, may improve treatment and create better patient outcomes.

Entities:  

Keywords:  T-cell lymphoma; candidemia; candidiasis; caspofungin; disseminated; pediatric; resistance

Year:  2018        PMID: 29441283      PMCID: PMC5803021          DOI: 10.21037/tp.2017.06.02

Source DB:  PubMed          Journal:  Transl Pediatr        ISSN: 2224-4336


  12 in total

1.  Generation of mutants in Candida albicans with reduced susceptibility to caspofungin: influence on other antifungal products.

Authors:  L Soler; J C Rodriguez; S Belda; R Cremades; M Ruiz-Garcia; P Lopez; G Royo
Journal:  J Chemother       Date:  2010-08       Impact factor: 1.714

2.  Micafungin twice weekly as antifungal prophylaxis in paediatric patients at high risk for invasive fungal disease.

Authors:  K Bochennek; A Balan; L Müller-Scholden; M Becker; F Farowski; C Müller; A H Groll; T Lehrnbecher
Journal:  J Antimicrob Chemother       Date:  2015-01-05       Impact factor: 5.790

Review 3.  Fungal infections in pediatric intensive care units.

Authors:  Gabriele Finco; Daniela Sanna; Maurizio Evangelista; Paolo Mura; Mario Musu
Journal:  J Matern Fetal Neonatal Med       Date:  2011-10

4.  Salvage therapy of refractory chronic disseminated candidiasis in a patient with acute myeloid leukaemia and secondary prophylaxis during allogeneic stem cell transplantation.

Authors:  Jörg J Vehreschild; Karsten Krüger; Oliver Kurzai; Claudia Wickenhauser; Karolin Behringer; Ulrich Töx; Oliver A Cornely
Journal:  Mycoses       Date:  2006       Impact factor: 4.377

5.  Chronic disseminated candidiasis in patients with hematologic malignancies. Clinical features and outcome of 29 episodes.

Authors:  Livio Pagano; Luca Mele; Luana Fianchi; Lorella Melillo; Bruno Martino; Domenico D'Antonio; Maria Elena Tosti; Brunella Posteraro; Maurizio Sanguinetti; Giulio Trapè; Francesco Equitani; Mario Carotenuto; Giuseppe Leone
Journal:  Haematologica       Date:  2002-05       Impact factor: 9.941

Review 6.  Candidemia in children.

Authors:  Theoklis Zaoutis
Journal:  Curr Med Res Opin       Date:  2010-07       Impact factor: 2.580

Review 7.  Chronic disseminated candidiasis in patients with acute leukemia: emphasis on diagnostic definition and treatment.

Authors:  Aisha Masood; Sabah Sallah
Journal:  Leuk Res       Date:  2004-12-30       Impact factor: 3.156

8.  Caspofungin-non-susceptible Candida isolates in cancer patients.

Authors:  Diamantis P Kofteridis; Russell E Lewis; Dimitrios P Kontoyiannis
Journal:  J Antimicrob Chemother       Date:  2009-12-16       Impact factor: 5.790

9.  Epidemiology and outcomes of candidemia in 2019 patients: data from the prospective antifungal therapy alliance registry.

Authors:  David L Horn; Dionissios Neofytos; Elias J Anaissie; Jay A Fishman; William J Steinbach; Ali J Olyaei; Kieren A Marr; Michael A Pfaller; Chi-Hsing Chang; Karen M Webster
Journal:  Clin Infect Dis       Date:  2009-06-15       Impact factor: 9.079

Review 10.  Patients at high risk of invasive fungal infections: when and how to treat.

Authors:  Maria J G T Rüping; Jörg J Vehreschild; Oliver A Cornely
Journal:  Drugs       Date:  2008       Impact factor: 9.546

View more
  1 in total

1.  Application of next generation sequencing-based rapid detection platform for microbiological diagnosis and drug resistance prediction in acute lower respiratory infection.

Authors:  Lingshan Chao; Jihong Li; Ya'nan Zhang; Hao Pu; Xixin Yan
Journal:  Ann Transl Med       Date:  2020-12
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.