Literature DB >> 29434388

Acute Hepatocellular Jaundice After Dofetilide Initiation: A Case Report.

Patrick Gary Rose1, Robert Seabury1, Gregory Cwikla1.   

Abstract

Dofetilide's hepatotoxicity is not well described. In this case report, we describe acute hepatocellular jaundice related to dofetilide use in a 33-year-old male being treated for atrial fibrillation. Both viral and ischemic causes of hepatocellular damage were ruled out as unlikely in this case. This case report outlines a rare yet probable report of idiosyncratic dofetilide-induced liver injury.

Entities:  

Keywords:  adverse drug reactions; adverse drug reactions reporting/monitoring; cardiac agents; cardiovascular; gastrointestinal disorders

Year:  2017        PMID： 29434388      PMCID： PMC5805014          DOI： 10.1177/0018578717738079

Source DB:  PubMed          Journal:  Hosp Pharm        ISSN： 0018-5787


  5 in total

Review 1.  Cardiovascular drugs. Dofetilide.

Authors:  J P Mounsey; J P DiMarco
Journal:  Circulation       Date:  2000-11-21       Impact factor: 29.690

2.  ACG Clinical Guideline: the diagnosis and management of idiosyncratic drug-induced liver injury.

Authors:  Naga P Chalasani; Paul H Hayashi; Herbert L Bonkovsky; Victor J Navarro; William M Lee; Robert J Fontana
Journal:  Am J Gastroenterol       Date:  2014-06-17       Impact factor: 10.864

3.  Significance of metabolism in the disposition and action of the antidysrhythmic drug, dofetilide. In vitro studies and correlation with in vivo data.

Authors:  D K Walker; C T Alabaster; G S Congrave; M B Hargreaves; R Hyland; B C Jones; L J Reed; D A Smith
Journal:  Drug Metab Dispos       Date:  1996-04       Impact factor: 3.922

4.  [Chronic hepatitis ascribed to the use of sotalol].

Authors:  A M Kootte; A R Janssens; D K Ouwehand; A M van Leeuwen
Journal:  Ned Tijdschr Geneeskd       Date:  2001-12-01

Review 5.  Mechanisms of drug-induced liver injury.

Authors:  Liyun Yuan; Neil Kaplowitz
Journal:  Clin Liver Dis       Date:  2013-08-01       Impact factor: 6.126
  5 in total
  1 in total

1.  Photosensitive nanocarriers for specific delivery of cargo into cells.

Authors:  Pedro Mena-Giraldo; Sandra Pérez-Buitrago; Maritza Londoño-Berrío; Isabel C Ortiz-Trujillo; Lina M Hoyos-Palacio; Jahir Orozco
Journal:  Sci Rep       Date:  2020-02-07       Impact factor: 4.379
  1 in total

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