Literature DB >> 29433991

Changes in volume, clinical practice and outcome after reorganisation of oesophago-gastric cancer care in England: A longitudinal observational study.

M Varagunam1, R Hardwick2, S Riley3, G Chadwick4, D A Cromwell5, O Groene6.   

Abstract

AIM: The centralisation of oesophago-gastric (O-G) cancer services in England was recommended in 2001, partly because of evidence for a volume-outcome effect for patients having surgery. This study investigated the changes in surgical services for O-G cancer and postoperative mortality since centralisation.
METHODS: Patients with O-G cancer who had an oesophageal or gastric resection between April 2003 and March 2014 were identified in the national Hospital Episodes Statistics database. We derived information on the number of NHS trusts performing surgery, their surgical volume, and the number of consultants operating. Postoperative mortality was measured at 30 days, 90 days and 1 year. Logistic regression was used to examine how surgical outcomes were related to patient characteristics and organisational variables.
RESULTS: During this period, 29 205 patients underwent an oesophagectomy or gastrectomy. The number of NHS trusts performing surgery decreased from 113 in 2003-04 to 43 in 2013-14, and the median annual surgical volume in NHS trusts rose from 21 to 55 patients. The annual 30 day, 90 day and 1 year mortality decreased from 7.4%, 11.3% and 29.7% in 2003-04 to 2.5%, 4.6% and 19.8% in 2013-14, respectively. There was no evidence that high-risk patients were not undergoing surgery. Changes in NHS trust volume explained only a small proportion of the observed fall in mortality.
CONCLUSION: Centralisation of surgical services for O-G cancer in England has resulted in lower postoperative mortality. This cannot be explained by increased volume alone.
Copyright © 2018 Elsevier Ltd, BASO ~ The Association for Cancer Surgery, and the European Society of Surgical Oncology. All rights reserved.

Entities:  

Keywords:  Cancer; Centralisation; Gastric; Oesophageal; Surgical outcomes

Mesh:

Year:  2018        PMID: 29433991     DOI: 10.1016/j.ejso.2018.01.001

Source DB:  PubMed          Journal:  Eur J Surg Oncol        ISSN: 0748-7983            Impact factor:   4.424


  10 in total

Review 1.  Regionalization of esophagectomy: where are we now?

Authors:  James M Clark; Daniel J Boffa; Robert A Meguid; Lisa M Brown; David T Cooke
Journal:  J Thorac Dis       Date:  2019-08       Impact factor: 2.895

2.  International Variation in Surgical Practices in Units Performing Oesophagectomy for Oesophageal Cancer: A Unit Survey from the Oesophago-Gastric Anastomosis Audit (OGAA).

Authors: 
Journal:  World J Surg       Date:  2019-11       Impact factor: 3.352

3.  Associations of centralization with health care quality for gastric cancer patients receiving gastrectomy in China.

Authors:  Jiafu Ji; Leiyu Shi; Xiangji Ying; Xinpu Lu; Fei Shan; Haibo Wang
Journal:  Chin J Cancer Res       Date:  2021-12-31       Impact factor: 5.087

4.  Single-centre review of the management of intra-thoracic oesophageal perforation in a tertiary oesophageal unit: paradigm shift, short- and long-term outcomes over 15 years.

Authors:  Vasileios Charalampakis; Victor Roth Cardoso; Rajwinder Nijjar; Rishi Singhal; Alistair Sharples; Maha Khalid; Luke Dickerson; Tom Wiggins; Georgios V Gkoutos; Olga Tucker; Paul Super; Martin Richardson
Journal:  Surg Endosc       Date:  2022-10-07       Impact factor: 3.453

Review 5.  Minimally invasive esophagectomy.

Authors:  Adam J Bograd; Daniela Molena
Journal:  Curr Probl Surg       Date:  2021-10-01       Impact factor: 2.815

6.  Regionalization of thoracic surgery improves short-term cancer esophagectomy outcomes.

Authors:  Sora Ely; Amy Alabaster; Simon K Ashiku; Ashish Patel; Jeffrey B Velotta
Journal:  J Thorac Dis       Date:  2019-05       Impact factor: 2.895

7.  Increased assessment of HER2 in metastatic gastroesophageal cancer patients: a nationwide population-based cohort study.

Authors:  Willemieke P M Dijksterhuis; Rob H A Verhoeven; Sybren L Meijer; Marije Slingerland; Nadia Haj Mohammad; Judith de Vos-Geelen; Laurens V Beerepoot; Theo van Voorthuizen; Geert-Jan Creemers; Martijn G H van Oijen; Hanneke W M van Laarhoven
Journal:  Gastric Cancer       Date:  2020-01-11       Impact factor: 7.370

8.  Impact of co-morbidity on reoperation or death within 90 days of surgery for oesophageal cancer.

Authors:  Z Cheng; A Johar; E Gottlieb-Vedi; M Nilsson; J Lagergren; P Lagergren
Journal:  BJS Open       Date:  2021-01-08

9.  Volume-outcome relationship in rectal cancer surgery.

Authors:  L Siragusa; B Sensi; D Vinci; M Franceschilli; C Pathirannehalage Don; G Bagaglini; V Bellato; M Campanelli; G S Sica
Journal:  Discov Oncol       Date:  2021-04-12

10.  Evaluation of oesophageal and gastric resection outcomes in a small-volume unit.

Authors:  Ahmed Hassn; Ashish Gupta; Mohamed Ramadan
Journal:  Ann Med Surg (Lond)       Date:  2021-06-11
  10 in total

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