Literature DB >> 29424644

Effectiveness of a monofilament wound debridement pad at removing biofilm and slough: ex vivo and clinical performance.

Gregory S Schultz1, Kevin Woo2, Dot Weir3, Qingping Yang4.   

Abstract

OBJECTIVE: Removal of slough and other devitalised tissue is an important step in biofilm-based wound care (BBWC) and wound bed preparation. Debridement is key to management of both slough and biofilm, and a number of methods are available to achieve this, including surgical/sharp and mechanical debridement. Developments have led to products indicated for debridement of wounds, including a sterile pad consisting of monofilament fibres. Our aim is to examine the effectiveness of a monofilament wound debridement pad (WDP), Debrisoft.
METHOD: We assessed the WDP, in laboratory tests, for the removal of mature biofilm from porcine dermal tissue in an ex vivo model, and the clinical management of sloughy wounds that would benefit from debridement. We used the UPPER score to determine the superficial infection status.
RESULTS: The WDP was effective in removing biofilm from porcine dermal tissue. A case series of 10 patients with chronic wounds suggested that the WDP was beneficial in the removal of slough. All chronic wounds had slough and were cleaned weekly, for four weeks, using the MDP to achieve improved healing and a clean wound bed. The average wound size decreased from 8.09cm2 at baseline to 2.3cm2 at week four, with three wounds healed completely. Exudate was reduced, and the UPPER score improved in every patient.
CONCLUSION: These results indicate that the WDP effectively debrides biofilm and slough, and contributes to care that follows the principles of wound bed preparation and BBWC.

Entities:  

Keywords:  biofilm; chronic wound; debridement; monofilament pad; slough; surgical wound

Mesh:

Year:  2018        PMID: 29424644     DOI: 10.12968/jowc.2018.27.2.80

Source DB:  PubMed          Journal:  J Wound Care        ISSN: 0969-0700            Impact factor:   2.072


  3 in total

1.  A comparative study on the cellular viability and debridement efficiency of antimicrobial-based wound dressings.

Authors:  Rui Chen; Anne-Marie Salisbury; Steven L Percival
Journal:  Int Wound J       Date:  2019-10-27       Impact factor: 3.315

Review 2.  [Position paper of the Initiative Chronische Wunde (ICW) e. V. on the nomenclature of debridement in chronic wounds].

Authors:  Joachim Dissemond; Anke Bültemann; Veronika Gerber; Martin Motzkus; Karl Christian Münter; Cornelia Erfurt-Berge
Journal:  Hautarzt       Date:  2022-01-24       Impact factor: 1.198

3.  Chronic wound biofilms: diagnosis and therapeutic strategies.

Authors:  Di Wei; Xiao-Mei Zhu; Yong-Yi Chen; Xu-Ying Li; Yu-Pan Chen; Hua-Yun Liu; Min Zhang
Journal:  Chin Med J (Engl)       Date:  2019-11-20       Impact factor: 2.628

  3 in total

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